Kuchuan Chen
Affiliations: | Boston Children's Hospital/Harvard Medical School |
Area:
NeuroscienceGoogle:
"Kuchuan Chen"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Hugo J. Bellen | grad student | Baylor College of Medicine | |
| Clifford Woolf | post-doc |
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Publications
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| Petrova V, Snavely AR, Splaine J, et al. (2024) Identification of novel neuroprotectants against vincristine-induced neurotoxicity in iPSC-derived neurons. Cellular and Molecular Life Sciences : Cmls. 81: 315 |
| Petrova V, Snavely AR, Splaine J, et al. (2024) Identification of novel neuroprotectants against vincristine-induced neurotoxicity in iPSC-derived neurons. Research Square |
| Huang X, Lee S, Chen K, et al. (2024) Downregulation of the silent potassium channel Kv8.1 increases motor neuron vulnerability in amyotrophic lateral sclerosis. Brain Communications. 6: fcae202 |
| Huang X, Roet KCD, Zhang L, et al. (2021) Human amyotrophic lateral sclerosis excitability phenotype screen: Target discovery and validation. Cell Reports. 35: 109224 |
| Klim JR, Williams LA, Limone F, et al. (2019) ALS-implicated protein TDP-43 sustains levels of STMN2, a mediator of motor neuron growth and repair. Nature Neuroscience |
| Lin G, Lee PT, Chen K, et al. (2018) Phospholipase PLA2G6, a Parkinsonism-Associated Gene, Affects Vps26 and Vps35, Retromer Function, and Ceramide Levels, Similar to α-Synuclein Gain. Cell Metabolism |
| Chen K, Ho TS, Lin G, et al. (2016) Loss of Frataxin activates the iron/sphingolipid/PDK1/Mef2 pathway in mammals. Elife. 5 |
| Chen K, Lin G, Haelterman NA, et al. (2016) Loss of Frataxin induces iron toxicity, sphingolipid synthesis, and Pdk1/Mef2 activation, leading to neurodegeneration. Elife. 5 |
| Li T, Fan J, Blanco-Sánchez B, et al. (2016) Ubr3, a Novel Modulator of Hh Signaling Affects the Degradation of Costal-2 and Kif7 through Poly-ubiquitination. Plos Genetics. 12: e1006054 |
| Ugur B, Chen K, Bellen HJ. (2016) Drosophila tools and assays for the study of human diseases. Disease Models & Mechanisms. 9: 235-44 |