Sandra J. Degen

Affiliations: 
Cincinnati Children's Hospital, Cincinnati, OH, United States 
Area:
blood coagulation, prothrombin, tPA
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Parents

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Russell F. Doolittle research assistant Cincinnati Children's Hospital
Earl W. Davie grad student 1982 University of Washington
 (Isolation and characterization of the human prothrombin gene and related genes.)
Edward Reich post-doc Cincinnati Children's Hospital
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Publications

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Mullins ES, Kombrinck KW, Talmage KE, et al. (2009) Genetic elimination of prothrombin in adult mice is not compatible with survival and results in spontaneous hemorrhagic events in both heart and brain. Blood. 113: 696-704
Mullins ES, Kombrinck KW, Talmage KE, et al. (2009) Genetic elimination of prothrombin in adult mice is not compatible with survival and results in spontaneous hemorrhagic events in both heart and brain Blood. 113: 696-704
Mullins ES, Kombrinck KW, Talmage KE, et al. (2008) Genetic Elimination of Prothrombin in Adult Mice Results in Fatal Spontaneous Hemorrhage in the Heart and Central Nervous System Blood. 112: 395-395
Wetzel CC, Leonis MA, Dent A, et al. (2007) Short-form Ron receptor is required for normal IFN-gamma production in concanavalin A-induced acute liver injury. American Journal of Physiology. Gastrointestinal and Liver Physiology. 292: G253-61
Mullins ES, Kombrinck KW, Flick MJ, et al. (2007) Reduction of Prothrombin in Mice Carrying a Conditional Knockout Allele Attenuates the Development of Paralysis Associated with Experimental Encephalitis. Blood. 110: 407-407
Mullins ES, Flick MJ, Kombrinck KW, et al. (2006) Conditional Disruption of the Murine Prothrombin Gene. Blood. 108: 1600-1600
Hess KA, Waltz SE, Toney-Earley K, et al. (2003) The receptor tyrosine kinase Ron is expressed in the mouse ovary and regulates inducible nitric oxide synthase levels and ovulation. Fertility and Sterility. 80: 747-54
Peace BE, Hill KJ, Degen SJ, et al. (2003) Cross-talk between the receptor tyrosine kinases Ron and epidermal growth factor receptor. Experimental Cell Research. 289: 317-25
Wetzel CC, Degen SJ, Waltz SE. (2003) Cis-acting elements in the hepatocyte growth factor-like protein gene regulate kidney and liver-specific expression in mice. Dna and Cell Biology. 22: 293-301
Hess KA, Waltz SE, Chan EL, et al. (2003) Receptor tyrosine kinase Ron is expressed in mouse reproductive tissues during embryo implantation and is important in trophoblast cell function. Biology of Reproduction. 68: 1267-75
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