Tyler Harpole

Affiliations: 
University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
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"Tyler Harpole"
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Harpole TJ, Grosman C. (2019) A Crucial Role for Side-Chain Conformation in the Versatile Charge Selectivity of Cys-Loop Receptors. Biophysical Journal
Fernández-Mariño AI, Harpole TJ, Oelstrom K, et al. (2018) Gating interaction maps reveal a noncanonical electromechanical coupling mode in the Shaker Kchannel. Nature Structural & Molecular Biology
Harpole TJ, Delemotte L. (2018) Conformational landscapes of membrane proteins delineated by enhanced sampling molecular dynamics simulations. Biochimica Et Biophysica Acta. Biomembranes. 1860: 909-926
Harpole TJ, Grosman C. (2016) Molecular Modeling of Charge Selectivity in Pentameric Ligand-Gated Ion Channels Biophysical Journal. 110: 602a
Harpole TJ, Grosman C. (2014) Side-chain conformation at the selectivity filter shapes the permeation free-energy landscape of an ion channel. Proceedings of the National Academy of Sciences of the United States of America. 111: E3196-205
Harpole TJ, Grosman C. (2014) Acidic Side-Chain Rotamers and their Impact on Ion Conduction through the Nicotinic Acetylcholine Receptor Biophysical Journal. 106: 339a
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