Lige Tonggu

Affiliations: 
University of Washington, Seattle, Seattle, WA 
Area:
Ion channel
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"Lige Tonggu"
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Publications

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Tonggu L, Wisedchaisri G, Gamal El-Din TM, et al. (2024) Dual receptor-sites reveal the structural basis for hyperactivation of sodium channels by poison-dart toxin batrachotoxin. Nature Communications. 15: 2306
Lenaeus M, Gamal El-Din TM, Tonggu L, et al. (2023) Structural basis for inhibition of the cardiac sodium channel by the atypical antiarrhythmic drug ranolazine. Nature Cardiovascular Research. 2: 587-594
Tonggu L, Wang L. (2022) Structure of the Human BK Ion Channel in Lipid Environment. Membranes. 12
Jiang D, Banh R, Gamal El-Din TM, et al. (2021) Open-state structure and pore gating mechanism of the cardiac sodium channel. Cell
Jiang D, Tonggu L, Gamal El-Din TM, et al. (2021) Structural basis for voltage-sensor trapping of the cardiac sodium channel by a deathstalker scorpion toxin. Nature Communications. 12: 128
Wisedchaisri G, Tonggu L, Gamal El-Din TM, et al. (2020) Structural Basis for High-Affinity Trapping of the Na1.7 Channel in Its Resting State by Tarantula Toxin. Molecular Cell
Jiang D, Shi H, Tonggu L, et al. (2019) Structure of the Cardiac Sodium Channel. Cell
Tonggu L, Wang L. (2019) Cryo-EM sample preparation method for extremely low concentration liposomes. Ultramicroscopy. 208: 112849
Wisedchaisri G, Tonggu L, McCord E, et al. (2019) Resting-State Structure and Gating Mechanism of a Voltage-Gated Sodium Channel. Cell
Tonggu L, Wang L. (2019) An Intermediate State of Human BK Channel Reconstituted in Liposomes Biophysical Journal. 116
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