Karina Jazmina Vargas, PhD

Affiliations: 
2003-2004 Physiology Austral University of Chile 
 2005-2009 Physiology and Biophysics University of Chile, Santiago, Región Metropolitana, Chile 
 2010-2017 Cell Biology Yale University, New Haven, CT 
 2018- Bell Center Marine Biological Laboratory Woods Hole 
Area:
Synaptic vesicles, Parkinson's disease, synuclein, endocytsosi
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Publications

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Wallace JN, Crockford ZC, Román-Vendrell C, et al. (2023) Excess Phosphoserine-129 α-Synuclein Induces Synaptic Vesicle Trafficking and Declustering Defects at a Vertebrate Synapse. Molecular Biology of the Cell. mbcE23070269
Vargas KJ, Colosi PL, Girardi E, et al. (2023) α-Synuclein colocalizes with AP180 and affects the size of clathrin lattices. The Journal of Biological Chemistry. 105091
Soll LG, Eisen JN, Vargas KJ, et al. (2020) α-Synuclein-112 Impairs Synaptic Vesicle Recycling Consistent With Its Enhanced Membrane Binding Properties. Frontiers in Cell and Developmental Biology. 8: 405
Vargas KJ. (2019) Kinetic Measurements of Endocytosis and Exocytosis in Cultured Neurons. Methods in Molecular Biology (Clifton, N.J.). 1948: 23-33
Vargas KJ, Schrod N, Davis T, et al. (2017) Synucleins Have Multiple Effects on Presynaptic Architecture. Cell Reports. 18: 161-173
Vargas KJ, Makani S, Davis T, et al. (2014) Synucleins regulate the kinetics of synaptic vesicle endocytosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 9364-76
Terunuma M, Vargas KJ, Wilkins ME, et al. (2010) Prolonged activation of NMDA receptors promotes dephosphorylation and alters postendocytic sorting of GABAB receptors. Proceedings of the National Academy of Sciences of the United States of America. 107: 13918-23
Ramírez OA, Vidal RL, Tello JA, et al. (2009) Dendritic assembly of heteromeric gamma-aminobutyric acid type B receptor subunits in hippocampal neurons. The Journal of Biological Chemistry. 284: 13077-85
Vargas KJ, Terunuma M, Tello JA, et al. (2008) The availability of surface GABA B receptors is independent of gamma-aminobutyric acid but controlled by glutamate in central neurons. The Journal of Biological Chemistry. 283: 24641-8
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