Kannan Kunchithapautham
Affiliations: | 2004-2015 | Intrexon |
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| Coughlin B, Schnabolk G, Joseph K, et al. (2016) Connecting the innate and adaptive immune responses in mouse choroidal neovascularization via the anaphylatoxin C5a and γδT-cells. Scientific Reports. 6: 23794 |
| Fields MA, Cai H, Bowrey HE, et al. (2015) Nitrite Modification of Extracellular Matrix Alters CD46 Expression and VEGF Release in Human Retinal Pigment Epithelium. Investigative Ophthalmology & Visual Science. 56: 4231-8 |
| Schnabolk G, Coughlin B, Joseph K, et al. (2015) Local production of the alternative pathway component factor B is sufficient to promote laser-induced choroidal neovascularization. Investigative Ophthalmology & Visual Science. 56: 1850-63 |
| Schnabolk G, Stauffer K, O'Quinn E, et al. (2014) A comparative analysis of C57BL/6J and 6N substrains; chemokine/cytokine expression and susceptibility to laser-induced choroidal neovascularization. Experimental Eye Research. 129: 18-23 |
| Kunchithapautham K, Atkinson C, Rohrer B. (2014) Smoke exposure causes endoplasmic reticulum stress and lipid accumulation in retinal pigment epithelium through oxidative stress and complement activation. The Journal of Biological Chemistry. 289: 14534-46 |
| Rohrer B, Kunchithapautham K, Genewsky A, et al. (2014) Prolonged SRC kinase activation, a mechanism to turn transient, sublytic complement activation into a sustained pathological condition in retinal pigment epithelium cells. Advances in Experimental Medicine and Biology. 801: 221-7 |
| Woodell A, Coughlin B, Kunchithapautham K, et al. (2013) Alternative complement pathway deficiency ameliorates chronic smoke-induced functional and morphological ocular injury. Plos One. 8: e67894 |
| Joseph K, Kulik L, Coughlin B, et al. (2013) Oxidative stress sensitizes retinal pigmented epithelial (RPE) cells to complement-mediated injury in a natural antibody-, lectin pathway-, and phospholipid epitope-dependent manner. The Journal of Biological Chemistry. 288: 12753-65 |
| Kunchithapautham K, Bandyopadhyay M, Dahrouj M, et al. (2012) Sublytic membrane-attack-complex activation and VEGF secretion in retinal pigment epithelial cells. Advances in Experimental Medicine and Biology. 723: 23-30 |
| Rohrer B, Kunchithapautham K, Genewski A, et al. (2012) Prolonged voltage-gated calcium channel activation by sublytic complement activation in retinal pigment epithelium, a mechanism for controlling VEGF secretion Immunobiology. 217: 1194-1195 |