Kristin Bigos

Johns Hopkins University, Baltimore, MD 
pharmacology, neuroimaging, genetics, psychiatry
"Kristin Bigos"
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Robert Bies grad student (PHTree)
Patricia D. Kroboth grad student (Chemistry Tree)
Bruce Pollock grad student University of Toronto (CAMH)
Daniel R. Weinberger post-doc
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Heide J, Zhang F, Bigos KL, et al. (2015) Differential Response to Risperidone in Schizophrenia Patients by KCNH2 Genotype and Drug Metabolizer Status. The American Journal of Psychiatry. appiajp201514050653
Dickinson D, Straub RE, Trampush JW, et al. (2014) Differential effects of common variants in SCN2A on general cognitive ability, brain physiology, and messenger RNA expression in schizophrenia cases and control individuals. Jama Psychiatry. 71: 647-56
Apud JA, Zhang F, Decot H, et al. (2012) Genetic variation in KCNH2 associated with expression in the brain of a unique hERG isoform modulates treatment response in patients with schizophrenia. The American Journal of Psychiatry. 169: 725-34
Bigos KL, Mattay VS, Callicott JH, et al. (2010) Genetic variation in CACNA1C affects brain circuitries related to mental illness. Archives of General Psychiatry. 67: 939-45
Bigos KL, Weinberger DR. (2010) Imaging genetics--days of future past. Neuroimage. 53: 804-9
Bigos KL, Pollock BG, Stankevich BA, et al. (2009) Sex differences in the pharmacokinetics and pharmacodynamics of antidepressants: an updated review. Gender Medicine. 6: 522-43
Rea RS, Capitano B, Bies R, et al. (2008) Suboptimal aminoglycoside dosing in critically ill patients. Therapeutic Drug Monitoring. 30: 674-81
Bigos KL, Pollock BG, Aizenstein HJ, et al. (2008) Acute 5-HT reuptake blockade potentiates human amygdala reactivity. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 3221-5
Bigos KL, Chew ML, Bies RR. (2008) Pharmacokinetics in geriatric psychiatry. Current Psychiatry Reports. 10: 30-6
Bigos KL, Pollock BG, Coley KC, et al. (2008) Sex, race, and smoking impact olanzapine exposure. Journal of Clinical Pharmacology. 48: 157-65
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