Varsha Shukla
Affiliations: | National Institutes of Health, Bethesda, MD |
Area:
NeurodegenerationGoogle:
"Varsha Shukla"Mean distance: 106866
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Publications
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| Binukumar BK, Skuntz S, Prochazkova M, et al. (2019) Overexpression of the Cdk5 inhibitory peptide in motor neurons rescue of amyotrophic lateral sclerosis phenotype in a mouse model. Human Molecular Genetics |
| Shukla V, Seo J, Binukumar BK, et al. (2017) TFP5, a Peptide Inhibitor of Aberrant and Hyperactive Cdk5/p25, Attenuates Pathological Phenotypes and Restores Synaptic Function in CK-p25Tg Mice. Journal of Alzheimer's Disease : Jad. 56: 335-349 |
| Amin ND, Zheng Y, Bk B, et al. (2016) The interaction of Munc 18 (p67) with the p10 domain of p35 protects in vivo Cdk5/p35 activity from inhibition by TFP5, a peptide derived from p35. Molecular Biology of the Cell |
| Binukumar BK, Pelech SL, Sutter C, et al. (2016) Profiling of p5, a 24 Amino Acid Inhibitory Peptide Derived from the CDK5 Activator, p35 CDKR1 Against 70 Protein Kinases. Journal of Alzheimer's Disease : Jad |
| Zheng YL, Zhang X, Fu HX, et al. (2016) Knockdown of Expression of Cdk5 or p35 (a Cdk5 Activator) Results in Podocyte Apoptosis. Plos One. 11: e0160252 |
| Binukumar BK, Shukla V, Amin ND, et al. (2015) Analysis of the Inhibitory Elements in the p5 Peptide Fragment of the CDK5 Activator, p35, CDKR1 Protein. Journal of Alzheimer's Disease : Jad |
| Bk B, Shukla V, Amin ND, et al. (2015) Peptide (TFP5/TP5), derived from Cdk5 activator P35, provides neuroprotection in the MPTP model of Parkinson's disease. Molecular Biology of the Cell |
| Binukumar BK, Zheng YL, Shukla V, et al. (2014) TFP5, a peptide derived from p35, a Cdk5 neuronal activator, rescues cortical neurons from glucose toxicity. Journal of Alzheimer's Disease : Jad. 39: 899-909 |
| Zheng YL, Li C, Hu YF, et al. (2013) Cdk5 inhibitory peptide (CIP) inhibits Cdk5/p25 activity induced by high glucose in pancreatic beta cells and recovers insulin secretion from p25 damage. Plos One. 8: e63332 |
| Binukumar BK, Shukla V, Amin ND, et al. (2013) Topographic regulation of neuronal intermediate filaments by phosphorylation, role of peptidyl-prolyl isomerase 1: significance in neurodegeneration. Histochemistry and Cell Biology. 140: 23-32 |