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Gary L Firestone, PhD

Affiliations: 
Cell Biology University of California, Berkeley, Berkeley, CA, United States 
Area:
Endocrinology
Website:
https://nst.berkeley.edu/users/gary-l-firestone
Google:
"Gary Lee Firestone"
Bio:

http://mcb.berkeley.edu/labs/firestone/index.html
https://scholar.google.com/citations?user=z5ovGi0AAAAJ&hl=en
https://medcom.uiowa.edu/biochem/category/biochemistry-hall-of-fame/edward-heath/

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Parents

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Edward Charles Heath grad student 1980 University of Iowa
 (Cyclic AMP dependent induction of alkaline phosphatase in mouse L cells.)
Keith  R. Yamamoto post-doc UCSF

Children

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Irma Sanchez grad student UC Berkeley
Lisa M. Bell grad student 2000 UC Berkeley
Yi Guan grad student 2002 UC Berkeley
Meredith L. Leong grad student 2002 UC Berkeley
Bridget A. O'Keeffe grad student 2003 UC Berkeley
Hanh H. Garcia grad student 2004 UC Berkeley
Nicola M. Rubenstein grad student 2004 UC Berkeley
Jocelyn C. Hsu grad student 2005 UC Berkeley
Kim L. Failor grad student 2007 UC Berkeley
Omar I. Vivar grad student 2007 UC Berkeley
Jamin A. Willoughby grad student 2007 UC Berkeley
Ida Aronchik grad student 2009 UC Berkeley
Crystal N. Marconett grad student 2009 UC Berkeley
Theresa R. Stueve grad student 2011 UC Berkeley
Bhumika Kapadia grad student 2013 UC Berkeley
Antony S. Tin grad student 2013 UC Berkeley

Collaborators

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Publications

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Kundu A, Khouri MG, Aryana S, et al. (2017) 1-Benzyl-indole-3-carbinol is a highly potent new small molecule inhibitor of Wnt/βcatenin signaling in melanoma cells that coordinately inhibits cell proliferation and disrupts expression of Microphthalmia Associated Transcription Factor isoform M. Carcinogenesis
Steely AM, Willoughby JA, Sundar SN, et al. (2017) Artemisinin disrupts androgen responsiveness of human prostate cancer cells by stimulating the 26S proteasome-mediated degradation of the androgen receptor protein. Anti-Cancer Drugs
Quirit JG, Lavrenov SN, Poindexter K, et al. (2016) Indole-3-carbinol (I3C) analogues are potent small molecule inhibitors of NEDD4-1 ubiquitin ligase activity that disrupt proliferation of human melanoma cells. Biochemical Pharmacology
Poindexter KM, Matthew S, Aronchik I, et al. (2016) Cooperative antiproliferative signaling by aspirin and indole-3-carbinol targets microphthalmia-associated transcription factor gene expression and promoter activity in human melanoma cells. Cell Biology and Toxicology
Kundu A, Quirit JG, Khouri MG, et al. (2016) Inhibition of oncogenic BRAF activity by indole-3-carbinol disrupts microphthalmia-associated transcription factor expression and arrests melanoma cell proliferation. Molecular Carcinogenesis
Yaswen P, MacKenzie KL, Keith WN, et al. (2015) Therapeutic targeting of replicative immortality. Seminars in Cancer Biology
Hargraves KG, He L, Firestone GL. (2015) Phytochemical regulation of the tumor suppressive microRNA, miR-34a, by p53-dependent and independent responses in human breast cancer cells. Molecular Carcinogenesis
Tin AS, Park AH, Sundar SN, et al. (2014) Essential role of the cancer stem/progenitor cell marker nucleostemin for indole-3-carbinol anti-proliferative responsiveness in human breast cancer cells. Bmc Biology. 12: 72
Firestone GL, Kapadia BJ. (2014) Minireview: Steroid/nuclear receptor-regulated dynamics of occluding and anchoring junctions. Molecular Endocrinology (Baltimore, Md.). 28: 1769-84
Aronchik I, Kundu A, Quirit JG, et al. (2014) The antiproliferative response of indole-3-carbinol in human melanoma cells is triggered by an interaction with NEDD4-1 and disruption of wild-type PTEN degradation. Molecular Cancer Research : McR. 12: 1621-34
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