Robert C. Monsen
Affiliations: | University of Louisville, Louisville, KY, United States |
Area:
G-quadruplex DNA, computational biophysics, drug discoveryGoogle:
"Robert Monsen"Mean distance: (not calculated yet)
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Publications
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| Monsen RC. (2023) Higher-order G-quadruplexes in promoters are untapped drug targets. Frontiers in Chemistry. 11: 1211512 |
| Monsen RC, Chua EYD, Hopkins JB, et al. (2023) Structure of a 28.5 kDa duplex-embedded G-quadruplex system resolved to 7.4 Å resolution with cryo-EM. Nucleic Acids Research |
| Monsen RC, Trent JO, Chaires JB. (2022) G-quadruplex DNA: A Longer Story. Accounts of Chemical Research |
| Monsen RC, Maguire JM, DeLeeuw LW, et al. (2022) Drug discovery of small molecules targeting the higher-order hTERT promoter G-quadruplex. Plos One. 17: e0270165 |
| Monsen RC, DeLeeuw LW, Dean WL, et al. (2022) Long promoter sequences form higher-order G-quadruplexes: an integrative structural biology study of c-Myc, k-Ras and c-Kit promoter sequences. Nucleic Acids Research. 50: 4127-4147 |
| DeLeeuw LW, Monsen RC, Petrauskas V, et al. (2021) POT1 stability and binding measured by fluorescence thermal shift assays. Plos One. 16: e0245675 |
| Monsen RC, Chakravarthy S, Dean WL, et al. (2021) The solution structures of higher-order human telomere G-quadruplex multimers. Nucleic Acids Research |
| Chaires JB, Gray RD, Dean WL, et al. (2020) Human POT1 unfolds G-quadruplexes by conformational selection. Nucleic Acids Research |
| Monsen RC, DeLeeuw L, Dean WL, et al. (2020) The hTERT core promoter forms three parallel G-quadruplexes. Nucleic Acids Research |
| Dean WL, Gray RD, DeLeeuw L, et al. (2019) Putting a New Spin of G-Quadruplex Structure and Binding by Analytical Ultracentrifugation. Methods in Molecular Biology (Clifton, N.J.). 2035: 87-103 |