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Christopher F. Higgins

Affiliations: 
Institute of Molecular Medicine University of Oxford, Oxford, United Kingdom 
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"Christopher Higgins"
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Parents

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Giovanna Ferro-Luzzi Ames post-doc (Cell Biology Tree)

Children

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Stephen J. Tucker grad student 1990-1993 Oxford

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Publications

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Patel DC, Pavitt D, Albrecht C, et al. (2008) Hyperglycaemic patients have decreased ATP-binding cassette transporter-A1 (ABCA-1) gene expression: A novel disease mechanism Atherosclerosis. 199: 231-232
Randle RA, Raguz S, Higgins CF, et al. (2007) Role of the highly structured 5'-end region of MDR1 mRNA in P-glycoprotein expression. The Biochemical Journal. 406: 445-55
Higgins CF. (2007) Multiple molecular mechanisms for multidrug resistance transporters. Nature. 446: 749-57
Weylandt KH, Nebrig M, Jansen-Rosseck N, et al. (2007) ClC-3 expression enhances etoposide resistance by increasing acidification of the late endocytic compartment. Molecular Cancer Therapeutics. 6: 979-86
Stieger B, Higgins CF. (2007) Twenty years of ATP-binding cassette (ABC) transporters. PflüGers Archiv : European Journal of Physiology. 453: 543
Linton KJ, Higgins CF. (2007) Structure and function of ABC transporters: the ATP switch provides flexible control. PflüGers Archiv : European Journal of Physiology. 453: 555-67
Okkenhaug H, Weylandt KH, Carmena D, et al. (2006) The human ClC-4 protein, a member of the CLC chloride channel/transporter family, is localized to the endoplasmic reticulum by its N-terminus. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 2390-2
Elliott JI, Surprenant A, Marelli-Berg FM, et al. (2005) Membrane phosphatidylserine distribution as a non-apoptotic signalling mechanism in lymphocytes. Nature Cell Biology. 7: 808-16
Albrecht C, McVey JH, Elliott JI, et al. (2005) A novel missense mutation in ABCA1 results in altered protein trafficking and reduced phosphatidylserine translocation in a patient with Scott syndrome. Blood. 106: 542-9
Begley GS, Horvath AR, Taylor JC, et al. (2005) Cytoplasmic domains of the transporter associated with antigen processing and P-glycoprotein interact with subunits of the proteasome. Molecular Immunology. 42: 137-41
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