Laszlo Urban
Affiliations: | Novartis, Basel, Basel-Stadt, France |
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Publications
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Pottel J, Armstrong D, Zou L, et al. (2020) The activities of drug inactive ingredients on biological targets. Science (New York, N.Y.). 369: 403-413 |
Maciejewski M, Lounkine E, Whitebread S, et al. (2017) Reverse translation of adverse event reports paves the way for de-risking preclinical off-targets. Elife. 6 |
Chen J, Varga A, Selvarajah S, et al. (2016) Spatial Distribution of the Cannabinoid Type 1 and Capsaicin Receptors May Contribute to the Complexity of Their Crosstalk. Scientific Reports. 6: 33307 |
White JP, Cibelli M, Urban L, et al. (2016) TRPV4: Molecular Conductor of a Diverse Orchestra. Physiological Reviews. 96: 911-73 |
Whitebread S, Dumotier B, Armstrong D, et al. (2016) Secondary pharmacology: screening and interpretation of off-target activities-focus on translation. Drug Discovery Today |
Sousa-Valente J, Andreou AP, Urban L, et al. (2014) Transient receptor potential ion channels in primary sensory neurons as targets for novel analgesics. British Journal of Pharmacology. 171: 2508-27 |
Urban L, Maciejewski M, Lounkine E, et al. (2014) Translation of off-target effects: Prediction of ADRs by integrated experimental and computational approach Toxicology Research. 3: 433-444 |
Lounkine E, Keiser MJ, Whitebread S, et al. (2012) Large-scale prediction and testing of drug activity on side-effect targets. Nature. 486: 361-7 |
Golden AP, Li N, Chen Q, et al. (2011) IonFlux: a microfluidic patch clamp system evaluated with human Ether-Ã -go-go related gene channel physiology and pharmacology. Assay and Drug Development Technologies. 9: 608-19 |
White JP, Urban L, Nagy I. (2011) TRPV1 function in health and disease. Current Pharmaceutical Biotechnology. 12: 130-44 |