Liaoyuan Hu
Affiliations: | Duke University, Durham, NC |
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Publications
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Wang J, Song X, Zhang D, et al. (2020) Cryo-EM structures of PAC1 receptor reveal ligand binding mechanism. Cell Research |
Ma Y, Ding Y, Song X, et al. (2020) Structure-guided discovery of a single-domain antibody agonist against human apelin receptor. Science Advances. 6: eaax7379 |
Chen X, Xu Y, Qu L, et al. (2019) Molecular Mechanism for Ligand Recognition and Subtype Selectivity of α Adrenergic Receptor. Cell Reports. 29: 2936-2943.e4 |
Ban T, Li X, Ma X, et al. (2018) GPCR structure and function relationship: identification of a biased apelin receptor mutant. The Biochemical Journal |
Hu LA, Zhou T, Ahn J, et al. (2009) Human and mouse trace amine-associated receptor 1 have distinct pharmacology towards endogenous monoamines and imidazoline receptor ligands. The Biochemical Journal. 424: 39-45 |
Hu LA, Tang PM, Eslahi NK, et al. (2009) Identification of surrogate agonists and antagonists for orphan G-protein-coupled receptor GPR139. Journal of Biomolecular Screening. 14: 789-97 |
Hu LA, Zhou T, Hamman BD, et al. (2008) A homogeneous G protein-coupled receptor ligand binding assay based on time-resolved fluorescence resonance energy transfer. Assay and Drug Development Technologies. 6: 543-50 |
Chen W, ten Berge D, Brown J, et al. (2003) Dishevelled 2 recruits beta-arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4. Science (New York, N.Y.). 301: 1391-4 |
Hu LA, Chen W, Martin NP, et al. (2003) GIPC interacts with the beta1-adrenergic receptor and regulates beta1-adrenergic receptor-mediated ERK activation. The Journal of Biological Chemistry. 278: 26295-301 |
Hu LA, Chen W, Premont RT, et al. (2002) G protein-coupled receptor kinase 5 regulates beta 1-adrenergic receptor association with PSD-95. The Journal of Biological Chemistry. 277: 1607-13 |