Trudy Kohout

Affiliations: 
Duke University, Durham, NC 
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"Trudy Kohout"
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Kohout TA, Xie Q, Reijmers S, et al. (2007) Trapping of a nonpeptide ligand by the extracellular domains of the gonadotropin-releasing hormone receptor results in insurmountable antagonism. Molecular Pharmacology. 72: 238-47
Gesty-Palmer D, El Shewy H, Kohout TA, et al. (2005) beta-Arrestin 2 expression determines the transcriptional response to lysophosphatidic acid stimulation in murine embryo fibroblasts. The Journal of Biological Chemistry. 280: 32157-67
Perry SJ, Junger S, Kohout TA, et al. (2005) Distinct conformations of the corticotropin releasing factor type 1 receptor adopted following agonist and antagonist binding are differentially regulated Journal of Biological Chemistry. 280: 11560-11568
Naik S, Billington CK, Pascual RM, et al. (2005) Regulation of cysteinyl leukotriene type 1 receptor internalization and signaling. The Journal of Biological Chemistry. 280: 8722-32
Kohout TA, Nicholas SL, Perry SJ, et al. (2004) Differential desensitization, receptor phosphorylation, β-arrestin recruitment, and ERK1/2 activation by the two endogenous ligands for the CC chemokine receptor 7 Journal of Biological Chemistry. 279: 23214-23222
Povsic TJ, Kohout TA, Lefkowitz RJ. (2003) Beta-arrestin1 mediates insulin-like growth factor 1 (IGF-1) activation of phosphatidylinositol 3-kinase (PI3K) and anti-apoptosis. The Journal of Biological Chemistry. 278: 51334-9
Azzi M, Charest PG, Angers S, et al. (2003) Beta-arrestin-mediated activation of MAPK by inverse agonists reveals distinct active conformations for G protein-coupled receptors. Proceedings of the National Academy of Sciences of the United States of America. 100: 11406-11
Vines CM, Revankar CM, Maestas DC, et al. (2003) N-formyl peptide receptors internalize but do not recycle in the absence of arrestins. The Journal of Biological Chemistry. 278: 41581-4
Wu JH, Peppel K, Nelson CD, et al. (2003) The adaptor protein beta-arrestin2 enhances endocytosis of the low density lipoprotein receptor. The Journal of Biological Chemistry. 278: 44238-45
Fraile-Ramos A, Kohout TA, Waldhoer M, et al. (2003) Endocytosis of the viral chemokine receptor US28 does not require beta-arrestins but is dependent on the clathrin-mediated pathway. Traffic (Copenhagen, Denmark). 4: 243-53
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