Billy Breton
Affiliations: | Biochemistry and Molecular Medicine | Université de Montréal, Montréal, Canada |
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| Wright SC, Avet C, Gaitonde SA, et al. (2024) Conformation- and activation-based BRET sensors differentially report on GPCR-G protein coupling. Science Signaling. 17: eadi4747 |
| Gross F, Mancini A, Breton B, et al. (2024) EGFR signaling and pharmacology in oncology revealed with innovative BRET-based biosensors. Communications Biology. 7: 250 |
| Heydenreich FM, Plouffe B, Rizk A, et al. (2022) . Molecular Pharmacology |
| Normand C, Breton B, Salze M, et al. (2022) A systematic analysis of prostaglandin E type 3 receptor isoform signaling reveals isoform- and species-dependent L798106 Gα-biased agonist responses. European Journal of Pharmacology. 927: 175043 |
| Avet C, Mancini A, Breton B, et al. (2022) Effector membrane translocation biosensors reveal G protein and βarrestin coupling profiles of 100 therapeutically relevant GPCRs. Elife. 11 |
| Stepniewski TM, Mancini A, Ågren R, et al. (2021) Mechanistic insights into dopaminergic and serotonergic neurotransmission - concerted interactions with helices 5 and 6 drive the functional outcome. Chemical Science. 12: 10990-11003 |
| Trauelsen M, Hiron TK, Lin D, et al. (2021) Extracellular succinate hyperpolarizes M2 macrophages through SUCNR1/GPR91-mediated Gq signaling. Cell Reports. 35: 109246 |
| Wright SC, Lukasheva V, Le Gouill C, et al. (2021) BRET-based effector membrane translocation assay monitors GPCR-promoted and endocytosis-mediated G activation at early endosomes. Proceedings of the National Academy of Sciences of the United States of America. 118 |
| Lukasheva V, Devost D, Le Gouill C, et al. (2020) Signal profiling of the βAR reveals coupling to novel signalling pathways and distinct phenotypic responses mediated by βAR and βAR. Scientific Reports. 10: 8779 |
| Mancini A, Avet C, Breton B, et al. (2020) Profiling the Signaling Repertoire of One Hundred Therapeutically‐Relevant Human GPCRs The Faseb Journal. 34: 1-1 |