Alan Hegron
Affiliations: | Biochemistry and Molecular Medicine | Université de Montréal, Montréal, Canada |
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Publications
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Gao W, Liu L, Huh E, et al. (2023) Human GLP1R variants affecting GLP1R cell surface expression are associated with impaired glucose control and increased adiposity. Nature Metabolism |
Hegron A, Peach CJ, Tonello R, et al. (2023) Therapeutic antagonism of the neurokinin 1 receptor in endosomes provides sustained pain relief. Proceedings of the National Academy of Sciences of the United States of America. 120: e2220979120 |
De Logu F, Nassini R, Hegron A, et al. (2022) Schwann cell endosome CGRP signals elicit periorbital mechanical allodynia in mice. Nature Communications. 13: 646 |
Latorre R, Hegron A, Peach CJ, et al. (2022) Mice expressing fluorescent PAR reveal that endocytosis mediates colonic inflammation and pain. Proceedings of the National Academy of Sciences of the United States of America. 119 |
Hegron A, Huh E, Deupi X, et al. (2021) Identification of Key Regions Mediating Human Melatonin Type 1 Receptor Functional Selectivity Revealed by Natural Variants. Acs Pharmacology & Translational Science. 4: 1614-1627 |
Jimenez-Vargas NN, Gong J, Wisdom MJ, et al. (2020) Endosomal signaling of delta opioid receptors is an endogenous mechanism and therapeutic target for relief from inflammatory pain. Proceedings of the National Academy of Sciences of the United States of America |
Hegron A, Jockers R. (2019) [In-depth analysis of the relationship between the MT receptor of melatonin and type 2 diabetes]. Medecine Sciences : M/S. 35: 412-416 |
Karamitri A, Plouffe B, Bonnefond A, et al. (2018) Type 2 diabetes-associated variants of the MT melatonin receptor affect distinct modes of signaling. Science Signaling. 11 |
Benleulmi-Chaachoua A, Hegron A, Le Boulch M, et al. (2018) Melatonin receptors limit dopamine reuptake by regulating dopamine transporter cell-surface exposure. Cellular and Molecular Life Sciences : Cmls |