Jacob K Sterling
Affiliations: | University of Pennsylvania, Philadelphia, PA, United States |
Area:
Retina, Glaucoma, Age-Related Macular Degeneration, Neurodegeneration, Cell BiologyGoogle:
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Publications
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Droho S, Voigt AP, Sterling JK, et al. (2023) NR4A1 deletion promotes pro-angiogenic polarization of macrophages derived from classical monocytes in a mouse model of neovascular age-related macular degeneration. Journal of Neuroinflammation. 20: 238 |
Zhang KR, Jankowski CSR, Marshall R, et al. (2023) Oxidative stress induces lysosomal membrane permeabilization and ceramide accumulation in retinal pigment epithelial cells. Disease Models & Mechanisms |
Lawrence ECN, Guo M, Schwartz TD, et al. (2023) Topical and systemic GLP-1R agonist administration both rescue retinal ganglion cells in hypertensive glaucoma. Frontiers in Cellular Neuroscience. 17: 1156829 |
Sterling JK, Baumann B, Foshe S, et al. (2022) Inflammatory adipose activates a nutritional immunity pathway leading to retinal dysfunction. Cell Reports. 39: 110942 |
Zhang KR, Baumann B, Song Y, et al. (2022) Conditional knockout of hephaestin in the neural retina disrupts retinal iron homeostasis. Experimental Eye Research. 218: 109028 |
Liu Y, Baumann B, Song Y, et al. (2022) Minimal effect of conditional ferroportin KO in the neural retina implicates ferrous iron in retinal iron overload and degeneration. Experimental Eye Research. 218: 108988 |
Sterling JK, Kam TI, Guttha S, et al. (2022) Interleukin-6 triggers toxic neuronal iron sequestration in response to pathological α-synuclein. Cell Reports. 38: 110358 |
Liu Y, Bell BA, Song Y, et al. (2021) Intraocular iron injection induces oxidative stress followed by elements of geographic atrophy and sympathetic ophthalmia. Aging Cell. e13490 |
Sterling J, Hua P, Dunaief JL, et al. (2021) Glucagon-like peptide 1 receptor agonist use is associated with reduced risk for glaucoma. The British Journal of Ophthalmology |
Sterling JK, Adetunji MO, Guttha S, et al. (2020) GLP-1 Receptor Agonist NLY01 Reduces Retinal Inflammation and Neuron Death Secondary to Ocular Hypertension. Cell Reports. 33: 108271 |