Tomasz Kos, PhD

Behavioral Neuroscience Institute of Pharmacology, Polish Academy of Sciences 
neuroscience, behavioral neuropharmacology, antidepressant pharmacology, rodent behavior, learning and memory, animal models of psychiatric disorders
"Tomasz Kos"
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Matloka M, Janowska S, Pankiewicz P, et al. (2022) A PDE10A inhibitor CPL500036 is a novel agent modulating striatal function devoid of most neuroleptic side-effects. Frontiers in Pharmacology. 13: 999685
Zajdel P, Grychowska K, Mogilski S, et al. (2021) Structure-Based Design and Optimization of FPPQ, a Dual-Acting 5-HT and 5-HT Receptor Antagonist with Antipsychotic and Procognitive Properties. Journal of Medicinal Chemistry
Kozela E, Krawczyk M, Kos T, et al. (2019) Cannabidiol Improves Cognitive Impairment and Reverses Cortical Transcriptional Changes Induced by Ketamine, in Schizophrenia-Like Model in Rats. Molecular Neurobiology
Zajdel P, Kos T, Marciniec K, et al. (2018) Novel multi-target azinesulfonamides of cyclic amine derivatives as potential antipsychotics with pro-social and pro-cognitive effects. European Journal of Medicinal Chemistry. 145: 790-804
Vanda D, Soural M, Canale V, et al. (2017) Novel non-sulfonamide 5-HT6 receptor partial inverse agonist in a group of imidazo[4,5-b]pyridines with cognition enhancing properties. European Journal of Medicinal Chemistry. 144: 716-729
Popik P, Hołuj M, Kos T, et al. (2017) Comparison of the Psychopharmacological Effects of Tiletamine and Ketamine in Rodents. Neurotoxicity Research
Zurawek D, Salerno-Kochan A, Dziedzicka-Wasylewska M, et al. (2017) Changes in the expression of metabotropic glutamate receptor 5 (mGluR5) in a ketamine-based animal model of schizophrenia. Schizophrenia Research
Canale V, Partyka A, Kurczab R, et al. (2017) Novel 5-HT7R antagonists, arylsulfonamide derivatives of (aryloxy)propyl piperidines: Add-on effect to the antidepressant activity of SSRI and DRI, and pro-cognitive profile. Bioorganic & Medicinal Chemistry
Cieślak PE, Llamosas N, Kos T, et al. (2017) The role of NMDA receptor-dependent activity of noradrenergic neurons in attention, impulsivity and exploratory behaviors. Genes, Brain, and Behavior
Potasiewicz A, Hołuj M, Kos T, et al. (2016) 3-Furan-2-yl-N-p-tolyl-acrylamide, a positive allosteric modulator of the α7 nicotinic receptor, reverses schizophrenia-like cognitive and social deficits in rats. Neuropharmacology
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