Christine Marx

Affiliations: 
Psychiatry University of North Carolina, Chapel Hill, Chapel Hill, NC 
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Parents

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A Leslie Morrow post-doc 1999-2001 UNC Chapel Hill
 (K award, residency fellowship, Duke faculty)
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Publications

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Marx CE, Bradford DW, Hamer RM, et al. (2011) Pregnenolone as a novel therapeutic candidate in schizophrenia: emerging preclinical and clinical evidence. Neuroscience. 191: 78-90
Marx CE, Keefe RS, Buchanan RW, et al. (2009) Proof-of-concept trial with the neurosteroid pregnenolone targeting cognitive and negative symptoms in schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 1885-903
Porcu P, O'Buckley TK, Alward SE, et al. (2009) Simultaneous quantification of GABAergic 3alpha,5alpha/3alpha,5beta neuroactive steroids in human and rat serum. Steroids. 74: 463-73
Wang C, Marx CE, Morrow AL, et al. (2007) Neurosteroid modulation of GABAergic neurotransmission in the central amygdala: a role for NMDA receptors. Neuroscience Letters. 415: 118-23
Marx CE, Shampine LJ, Khisti RT, et al. (2006) Olanzapine and fluoxetine administration and coadministration increase rat hippocampal pregnenolone, allopregnanolone and peripheral deoxycorticosterone: implications for therapeutic actions. Pharmacology, Biochemistry, and Behavior. 84: 609-17
Marx CE, Shampine LJ, Duncan GE, et al. (2006) Clozapine markedly elevates pregnenolone in rat hippocampus, cerebral cortex, and serum: candidate mechanism for superior efficacy? Pharmacology, Biochemistry, and Behavior. 84: 598-608
Pierucci-Lagha A, Covault J, Feinn R, et al. (2006) Subjective effects and changes in steroid hormone concentrations in humans following acute consumption of alcohol. Psychopharmacology. 186: 451-61
Marx CE, Stevens RD, Shampine LJ, et al. (2006) Neuroactive steroids are altered in schizophrenia and bipolar disorder: relevance to pathophysiology and therapeutics. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 1249-63
Marx CE, Grobin AC, Deutch AY, et al. (2005) Chapter 3.5 Atypical antipsychotic drugs and stress Techniques in the Behavioral and Neural Sciences. 15: 301-313
Marx CE, VanDoren MJ, Duncan GE, et al. (2003) Olanzapine and clozapine increase the GABAergic neuroactive steroid allopregnanolone in rodents. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 1-13
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