Eric A. Gaucher
Affiliations: | Georgia Institute of Technology, Atlanta, GA |
Area:
molecular evolutionGoogle:
"Eric Gaucher"Children
Sign in to add trainee| Christina L Graves | research assistant | 2009-2011 | Georgia Tech (Neurotree) |
| Zane Wolf | research assistant | 2015-2015 | Georgia Tech (Biomechanics Tree) |
| Lake Li | grad student | ||
| Zi-Ming Zhao | grad student | 2012 | Georgia Tech |
| Megan F. Cole | post-doc | Georgia Tech | |
| Betul Kacar | post-doc | Georgia Tech |
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Publications
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| Gamiz-Arco G, Risso VA, Gaucher EA, et al. (2021) Combining Ancestral Reconstruction with Folding-Landscape Simulations to Engineer Heterologous Protein Expression. Journal of Molecular Biology. 433: 167321 |
| Knight KA, Coyle CW, Radford CE, et al. (2021) Identification of coagulation factor IX variants with enhanced activity through ancestral sequence reconstruction. Blood Advances. 5: 3333-3343 |
| Zakas PM, Coyle CW, Brehm A, et al. (2021) Molecular coevolution of coagulation factor VIII and von Willebrand factor. Blood Advances. 5: 812-822 |
| Selberg AGA, Gaucher EA, Liberles DA. (2021) Ancestral Sequence Reconstruction: From Chemical Paleogenetics to Maximum Likelihood Algorithms and Beyond. Journal of Molecular Evolution |
| DeLey Cox VE, Cole MF, Gaucher EA. (2019) Incorporation of Modified Amino Acids by Engineered Elongation Factors with Expanded Substrate Capabilities. Acs Synthetic Biology. 8: 287-296 |
| Okafor CD, Pathak MC, Fagan CE, et al. (2018) Structural and Dynamics Comparison of Thermostability in Ancient, Modern, and Consensus Elongation Factor Tus. Structure (London, England : 1993). 26: 118-129.e3 |
| Risso VA, Martinez-Rodriguez S, Candel AM, et al. (2017) De novo active sites for resurrected Precambrian enzymes. Nature Communications. 8: 16113 |
| Kacar B, Ge X, Sanyal S, et al. (2017) Experimental Evolution of Escherichia coli Harboring an Ancient Translation Protein. Journal of Molecular Evolution |
| Zakas PM, Brown HC, Knight K, et al. (2016) Enhancing the pharmaceutical properties of protein drugs by ancestral sequence reconstruction. Nature Biotechnology |
| Randall RN, Radford CE, Roof KA, et al. (2016) An experimental phylogeny to benchmark ancestral sequence reconstruction. Nature Communications. 7: 12847 |