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Andrew Koob

Affiliations: 
University of Hartford, West Hartford, CT, United States 
Area:
astrocytes, neurodegenerative disease
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"Andrew Koob"
Mean distance: 16.85 (cluster 32)
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Parents

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Richard Borgens grad student 2001-2005 Purdue
Ann-Christine Duhaime post-doc 2005-2006 Dartmouth

Children

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Cynthia Winham grad student 2017-2018 University of Hartford
Timmy Le grad student 2018-2019 University of Hartford

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Publications

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Andromidas F, Mackinnon BE, Myers AJ, et al. (2024) Astrocytes initiate autophagic flux and maintain cell viability after internalizing non-active native extracellular α-synuclein. Molecular and Cellular Neurosciences. 131: 103975
Myers AJ, Brahimi A, Jenkins IJ, et al. (2023) The Synucleins and the Astrocyte. Biology. 12
Andromidas F, Atashpanjeh S, Myers AJ, et al. (2021) The Astrogenic Balance in the Aging Brain. Current Neuropharmacology
Le T, Winham CL, Andromidas F, et al. (2020) Chimera RNA interference knockdown of γ-synuclein in human cortical astrocytes results in mitotic catastrophe. Neural Regeneration Research. 15: 1894-1902
Winham CL, Le T, Jellison ER, et al. (2019) γ-Synuclein Induces Human Cortical Astrocyte Proliferation and Subsequent BDNF Expression and Release. Neuroscience. 410: 41-54
Mohn TC, Koob AO. (2015) Adult Astrogenesis and the Etiology of Cortical Neurodegeneration. Journal of Experimental Neuroscience. 9: 25-34
Koob AO, Shaked GM, Bender A, et al. (2014) Neurogranin binds α-synuclein in the human superior temporal cortex and interaction is decreased in Parkinson's disease. Brain Research. 1591: 102-10
Bender A, Desplats P, Spencer B, et al. (2013) TOM40 mediates mitochondrial dysfunction induced by α-synuclein accumulation in Parkinson's disease. Plos One. 8: e62277
Koob AO, Bruns L, Prassler C, et al. (2012) Protein analysis through Western blot of cells excised individually from human brain and muscle tissue. Analytical Biochemistry. 425: 120-4
Koob AO, Ubhi K, Paulsson JF, et al. (2010) Lovastatin ameliorates alpha-synuclein accumulation and oxidation in transgenic mouse models of alpha-synucleinopathies. Experimental Neurology. 221: 267-74
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