Katie Copley

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2019- University of Pennsylvania, Philadelphia, PA, United States 
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"Katie Copley"
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Sweeney KM, Chantarawong S, Barbieri EM, et al. (2024) CRISPR screen for protein inclusion formation uncovers a role for SRRD in the regulation of intermediate filament dynamics and aggresome assembly. Plos Genetics. 20: e1011138
Guo L, Mann JR, Mauna JC, et al. (2023) Defining RNA oligonucleotides that reverse deleterious phase transitions of RNA-binding proteins with prion-like domains. Biorxiv : the Preprint Server For Biology
Ervilha Pereira P, Schuermans N, Meylemans A, et al. (2023) C-terminal frameshift variant of TDP-43 with pronounced aggregation-propensity causes rimmed vacuole myopathy but not ALS/FTD. Acta Neuropathologica
Copley KE, Shorter J. (2023) Repetitive elements in aging and neurodegeneration. Trends in Genetics : Tig
Gleixner AM, Verdone BM, Otte CG, et al. (2022) NUP62 localizes to ALS/FTLD pathological assemblies and contributes to TDP-43 insolubility. Nature Communications. 13: 3380
Shen H, Yanas A, Owens MC, et al. (2022) Sexually dimorphic RNA helicases DDX3X and DDX3Y differentially regulate RNA metabolism through phase separation. Molecular Cell
Copley KE, Shorter J. (2022) Flying under the radar: TMEM106B(120-254) fibrils break out in diverse neurodegenerative disorders. Cell. 185: 1290-1292
Hallegger M, Chakrabarti AM, Lee FCY, et al. (2021) TDP-43 condensation properties specify its RNA-binding and regulatory repertoire. Cell
Mann JR, Gleixner AM, Mauna JC, et al. (2019) RNA Binding Antagonizes Neurotoxic Phase Transitions of TDP-43. Neuron
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