Steven Boeynaems
Affiliations: | Stanford University Medical School |
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Boeynaems S, Dorone Y, Zhuang Y, et al. (2023) Poly(A)-binding protein is an ataxin-2 chaperone that regulates biomolecular condensates. Molecular Cell |
Boeynaems S, Ma XR, Yeong V, et al. (2023) Aberrant phase separation is a common killing strategy of positively charged peptides in biology and human disease. Biorxiv : the Preprint Server For Biology |
Kim G, Nakayama L, Blum JA, et al. (2022) Genome-wide CRISPR screen reveals v-ATPase as a drug target to lower levels of ALS protein ataxin-2. Cell Reports. 41: 111508 |
Lasker K, Boeynaems S, Lam V, et al. (2022) The material properties of a bacterial-derived biomolecular condensate tune biological function in natural and synthetic systems. Nature Communications. 13: 5643 |
Boeynaems S, Gitler AD. (2022) You come at the misfolded proteins, you best not miss. Trends in Biochemical Sciences. 47: 1-2 |
Dorone Y, Boeynaems S, Flores E, et al. (2021) A prion-like protein regulator of seed germination undergoes hydration-dependent phase separation. Cell |
Friedman AK, Boeynaems S, Baker LA. (2021) Synthetic hydrogel mimics of the nuclear pore complex for the study of nucleocytoplasmic transport defects in C9orf72 ALS/FTD. Analytical and Bioanalytical Chemistry |
Fumagalli L, Young FL, Boeynaems S, et al. (2021) -derived arginine-containing dipeptide repeats associate with axonal transport machinery and impede microtubule-based motility. Science Advances. 7 |
Fazal R, Boeynaems S, Swijsen A, et al. (2021) HDAC6 inhibition restores TDP-43 pathology and axonal transport defects in human motor neurons with TARDBP mutations. The Embo Journal. e106177 |
Gittings LM, Boeynaems S, Lightwood D, et al. (2019) Symmetric dimethylation of poly-GR correlates with disease duration in C9orf72 FTLD and ALS and reduces poly-GR phase separation and toxicity. Acta Neuropathologica |