Fraser J Sim

Affiliations: 
Pharmacology & Toxicology University at Buffalo Jacobs School of Medicine and Biomedical Sciences 
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Evans LMP, Gawron J, Sim FJ, et al. (2024) Human iPSC-derived myelinating organoids and globoid cells to study Krabbe disease. Plos One. 19: e0314858
Weaver MR, Shkoruta D, Pellegatta M, et al. (2024) The STRIPAK complex is required for radial sorting and laminin receptor expression in Schwann cells. Biorxiv : the Preprint Server For Biology
Cooper JJM, Muthaiah R, Frost JR, et al. (2024) Clemastine Induces Oligodendrocyte Progenitor Pool Exhaustion and Senescence in the Context of Chronic Demyelination in a Rabbit Model. Annals of Neurology
Evans LMP, Gawron J, Sim FJ, et al. (2024) Human iPSC-derived myelinating organoids and globoid cells to study Krabbe Disease. Biorxiv : the Preprint Server For Biology
Kumar Podder A, Mohamed MA, Seidman RA, et al. (2024) Injectable shear-thinning hydrogels promote oligodendrocyte progenitor cell survival and remyelination in the central nervous system. Science Advances. 10: eadk9918
Ravichandar R, Gadelkarim F, Muthaiah R, et al. (2024) Dysregulated cholinergic signaling inhibits oligodendrocyte maturation following demyelination. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience
Marziali LN, Hwang Y, Palmisano M, et al. (2023) p38γ MAPK delays myelination and remyelination and is abundant in multiple sclerosis lesions. Brain : a Journal of Neurology
Cooper JJM, Polanco JJ, Saraswat D, et al. (2022) Chronic demyelination of rabbit lesions is attributable to failed oligodendrocyte progenitor cell repopulation. Glia
Seidman RA, Khattab H, Polanco JJ, et al. (2022) Oscillatory calcium release and sustained store-operated oscillatory calcium signaling prevents differentiation of human oligodendrocyte progenitor cells. Scientific Reports. 12: 6160
Saraswat D, Shayya HJ, Polanco JJ, et al. (2021) Overcoming the inhibitory microenvironment surrounding oligodendrocyte progenitor cells following experimental demyelination. Nature Communications. 12: 1923
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