George Yancopoulos, MD, PhD

Regeneron, Rensselaer, NY, United States 
"George Yancopoulos"
Mean distance: 16.75 (cluster 31)
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Xin Y, Okamoto H, Kim J, et al. (2016) Single-Cell RNAseq Reveals That Pancreatic β-Cells From Very Old Male Mice Have a Young Gene Signature. Endocrinology. en20161235
Wenzel S, Castro M, Corren J, et al. (2016) Dupilumab efficacy and safety in adults with uncontrolled persistent asthma despite use of medium-to-high-dose inhaled corticosteroids plus a long-acting β2 agonist: a randomised double-blind placebo-controlled pivotal phase 2b dose-ranging trial. Lancet (London, England)
Harp JB, Yancopoulos GD, Gromada J. (2016) Glucagon Orchestrates Stress-induced Hyperglycemia. Diabetes, Obesity & Metabolism
Atanasio A, Decman V, White D, et al. (2016) C9orf72 ablation causes immune dysregulation characterized by leukocyte expansion, autoantibody production, and glomerulonephropathy in mice. Scientific Reports. 6: 23204
Xin Y, Kim J, Ni M, et al. (2016) Use of the Fluidigm C1 platform for RNA sequencing of single mouse pancreatic islet cells. Proceedings of the National Academy of Sciences of the United States of America
Dewey FE, Gusarova V, O'Dushlaine C, et al. (2016) Inactivating Variants in ANGPTL4 and Risk of Coronary Artery Disease. The New England Journal of Medicine
Eichten A, Su J, Adler A, et al. (2016) Resistance to anti-VEGF therapy mediated by autocrine IL-6/STAT3 signaling and overcome by IL-6 blockade. Cancer Research
Bachert C, Mannent L, Naclerio RM, et al. (2016) Effect of Subcutaneous Dupilumab on Nasal Polyp Burden in Patients With Chronic Sinusitis and Nasal Polyposis: A Randomized Clinical Trial. Jama. 315: 469-79
Smith EJ, Olson K, Haber LJ, et al. (2015) A novel, native-format bispecific antibody triggering T-cell killing of B-cells is robustly active in mouse tumor models and cynomolgus monkeys. Scientific Reports. 5: 17943
Gandhi NA, Bennett BL, Graham NM, et al. (2015) Targeting key proximal drivers of type 2 inflammation in disease. Nature Reviews. Drug Discovery
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