Thomas Baukrowitz
Affiliations: | Physiology | Christian-Albrechts-Universität zu Kiel, Kiel, Schleswig-Holstein, Germany |
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| Hall PR, Jouen-Tachoire T, Schewe M, et al. (2024) Structures of TASK-1 and TASK-3 K2P channels provide insight into their gating and dysfunction in disease. Structure (London, England : 1993) |
| Türkaydin B, Schewe M, Riel EB, et al. (2024) Atomistic mechanism of coupling between cytosolic sensor domain and selectivity filter in TREK K2P channels. Nature Communications. 15: 4628 |
| Rödström KEJ, Cloake A, Sörmann J, et al. (2024) Extracellular modulation of TREK-2 activity with nanobodies provides insight into the mechanisms of K2P channel regulation. Nature Communications. 15: 4173 |
| Schroeter CB, Nelke C, Schewe M, et al. (2023) Validation of TREK1 ion channel activators as an immunomodulatory and neuroprotective strategy in neuroinflammation. Biological Chemistry. 404: 355-375 |
| Sörmann J, Schewe M, Proks P, et al. (2022) Gain-of-function mutations in KCNK3 cause a developmental disorder with sleep apnea. Nature Genetics. 54: 1534-1543 |
| Riel EB, Jürs BC, Cordeiro S, et al. (2022) The versatile regulation of K2P channels by polyanionic lipids of the phosphoinositide and fatty acid metabolism. The Journal of General Physiology. 154 |
| Chang WW, Matt AS, Schewe M, et al. (2021) An otopetrin family proton channel promotes cellular acid efflux critical for biomineralization in a marine calcifier. Proceedings of the National Academy of Sciences of the United States of America. 118 |
| Proks P, Schewe M, Conrad LJ, et al. (2021) Norfluoxetine inhibits TREK-2 K2P channels by multiple mechanisms including state-independent effects on the selectivity filter gate. The Journal of General Physiology. 153 |
| Schewe M, Riel EB, Rinné S, et al. (2021) Structural Basis for Gating of the Two-Pore Domain K+ (K2P) Channels TASK-1 and TALK-2 Biophysical Journal. 120: 289a |
| Riel EB, Jürs B, Langer J, et al. (2020) Characterisation of the Versatile Gating Behaviour in Talk-2 K2P Channels Biophysical Journal. 118: 269a |