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Brandon C. McKinney, M.D., Ph.D.

Affiliations: 
2010- Psychiatry University of Pittsburgh School of Medicine, Pittsburgh, PA, United States 
Area:
schizophrenia, aging, epigenetic, DNA methylation
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"Brandon McKinney"
Mean distance: 14.15 (cluster 19)
 		SNBCP
Cross-listing: MichiganTree

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Parents

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William T. Greenough grad student 2001-2002 UIUC
Geoffrey G. Murphy grad student 2004-2010 University of Michigan
 (L -type voltage -gated calcium channels in fear conditioning, fear extinction, and amygdala neurophysiology.)
Etienne Sibille post-doc 2010-2014 University of Pittsburgh, School of Medicine
Robert Sweet post-doc 2014-2016 University of Pittsburgh, School of Medicine

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Publications

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DeGiosio RA, Grubisha MJ, MacDonald ML, et al. (2022) More than a marker: potential pathogenic functions of MAP2. Frontiers in Molecular Neuroscience. 15: 974890
McKinney BC, McClain LL, Hensler CM, et al. (2022) Schizophrenia-associated differential DNA methylation in brain is distributed across the genome and annotated to MAD1L1, a locus at which DNA methylation and transcription phenotypes share genetic variation with schizophrenia risk. Translational Psychiatry. 12: 340
McKinney B, Hensler C, Kuflewski J, et al. (2020) Using a CRISPR/Cas9-Based Epigenetic Editing Tool to Study the Cell-Type-Specific Effects of the DNA Methylation Alterations Observed in the Auditory Cortex Subjects With Schizophrenia Biological Psychiatry. 87: S61
Hensler C, Kuflewski J, Sweet R, et al. (2020) Writing DNA Methylation at Dendritic Spine-Associated Locus via CRISPR/dCas9 Biological Psychiatry. 87: S241-S242
McKinney BC, MacDonald ML, Newman JT, et al. (2019) Density of small dendritic spines and microtubule-associated-protein-2 immunoreactivity in the primary auditory cortex of subjects with schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology
McKinney BC, Lin CW, Rahman T, et al. (2019) DNA methylation in the human frontal cortex reveals a putative mechanism for age-by-disease interactions. Translational Psychiatry. 9: 39
Kuflewski J, Hensler C, Tariq S, et al. (2019) F165. Using CRISPR/Cas9-Based Epigenetic Editing to Study the Role of Schizophrenia-Related Alterations in DNA Methylation on Dendritic Spine Density Biological Psychiatry. 85
McKinney B, Kuflewski J, Ding Y, et al. (2018) T203. Methylation and Transcription of BAIAP2 and DLG1, Regulators of Dendritic Spine Structure and Function, in the Postmortem Brain of Schizophrenia Subjects Biological Psychiatry. 83
McKinney BC, Lin H, Ding Y, et al. (2017) DNA methylation age is not accelerated in brain or blood of subjects with schizophrenia. Schizophrenia Research
McKinney BC, Lin H, Ding Y, et al. (2017) DNA methylation evidence against the accelerated aging hypothesis of schizophrenia. Npj Schizophrenia. 3: 13
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