Xiaoguang Li
Affiliations: | 2015-2021 | SBP Medical Discovery Institute |
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Publications
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| Wang X, Xie J, Tan L, et al. (2023) N6-methyladenosine-modified circRIMS2 mediates synaptic and memory impairments by activating GluN2B ubiquitination in Alzheimer's disease. Translational Neurodegeneration. 12: 53 |
| Jiang L, Li X, Myers S, et al. (2021) Astroglial ER protein Membralin is an essential neuroinflammation regulator. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 17: e058566 |
| Liu T, Zhu B, Liu Y, et al. (2020) Multi-omic comparison of Alzheimer's variants in human ESC-derived microglia reveals convergence at APOE. The Journal of Experimental Medicine. 217 |
| Feng Q, Luo Y, Zhang XN, et al. (2019) MAPT/Tau accumulation represses autophagy flux by disrupting IST1-regulated ESCRT-III complex formation: a vicious cycle in Alzheimer neurodegeneration. Autophagy |
| Jiang LL, Zhu B, Zhao Y, et al. (2019) Membralin deficiency dysregulates astrocytic glutamate homeostasis leading to ALS-like impairment. The Journal of Clinical Investigation. 130 |
| Li XG, Hong XY, Wang YL, et al. (2019) Tau accumulation triggers STAT1-dependent memory deficits by suppressing NMDA receptor expression. Embo Reports |
| Zhang Z, Li XG, Wang ZH, et al. (2018) δ-Secretase-cleaved Tau stimulates Aβ production via upregulating STAT1-BACE1 signaling in Alzheimer's disease. Molecular Psychiatry |
| Gao Y, Liu EJ, Wang WJ, et al. (2018) Microglia CREB-Phosphorylation Mediates Amyloid-β-Induced Neuronal Toxicity. Journal of Alzheimer's Disease : Jad |
| Lee CYD, Daggett A, Gu X, et al. (2018) Elevated TREM2 Gene Dosage Reprograms Microglia Responsivity and Ameliorates Pathological Phenotypes in Alzheimer's Disease Models. Neuron. 97: 1032-1048.e5 |
| Zhao Y, Wu X, Li X, et al. (2018) TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function. Neuron. 97: 1023-1031.e7 |