Aislinn Williams, MD/PhD
Affiliations: | Psychiatry | University of Michigan, Ann Arbor, Ann Arbor, MI |
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Parents
Sign in to add mentorBeverly L. Davidson | grad student | 2010 | University of Iowa | |
(Toxic intermediates and protein quality control in the polyglutamine disease, SCA3.) |
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Publications
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Williams AJ, Knutson TM, Colomer Gould VF, et al. (2009) In vivo suppression of polyglutamine neurotoxicity by C-terminus of Hsp70-interacting protein (CHIP) supports an aggregation model of pathogenesis. Neurobiology of Disease. 33: 342-53 |
Williams AJ, Paulson HL. (2008) Polyglutamine neurodegeneration: protein misfolding revisited. Trends in Neurosciences. 31: 521-8 |
Miller VM, Nelson RF, Gouvion CM, et al. (2005) CHIP suppresses polyglutamine aggregation and toxicity in vitro and in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 9152-61 |
Chai Y, Shao J, Miller VM, et al. (2002) Live-cell imaging reveals divergent intracellular dynamics of polyglutamine disease proteins and supports a sequestration model of pathogenesis. Proceedings of the National Academy of Sciences of the United States of America. 99: 9310-5 |