Arthur M. Brown

ChanTest, Garfield Heights, OH, United States 
Ion Channels
"Arthur Brown"
Mean distance: 17.83 (cluster 11)


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Eric Neil grad student 1961-1964 Middlesex Hospital Medical School (Physiology Academic Tree)


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Paola Perin research assistant 1993-1994 Baylor
Michael C. Andresen grad student 1975-1978 UTMB
Laura Bianchi grad student 1994-1998
Mariella De Biasi post-doc Baylor
Michael C. Andresen post-doc 1977-1979 UTMB
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Brown AM. (2005) HERG block, QT liability and sudden cardiac death. Novartis Foundation Symposium. 266: 118-31; discussion 1
Ficker E, Dennis A, Kuryshev Y, et al. (2005) HERG channel trafficking. Novartis Foundation Symposium. 266: 57-69; discussion 70
Kirsch GE, Trepakova ES, Brimecombe JC, et al. (2004) Variability in the measurement of hERG potassium channel inhibition: effects of temperature and stimulus pattern. Journal of Pharmacological and Toxicological Methods. 50: 93-101
Ficker E, Kuryshev YA, Dennis AT, et al. (2004) Mechanisms of arsenic-induced prolongation of cardiac repolarization. Molecular Pharmacology. 66: 33-44
Ficker E, Dennis AT, Wang L, et al. (2003) Role of the cytosolic chaperones Hsp70 and Hsp90 in maturation of the cardiac potassium channel HERG. Circulation Research. 92: e87-100
Wible BA, Wang L, Kuryshev YA, et al. (2002) Increased K+ efflux and apoptosis induced by the potassium channel modulatory protein KChAP/PIAS3beta in prostate cancer cells. The Journal of Biological Chemistry. 277: 17852-62
Ficker E, Obejero-Paz CA, Zhao S, et al. (2002) The binding site for channel blockers that rescue misprocessed human long QT syndrome type 2 ether-a-gogo-related gene (HERG) mutations. The Journal of Biological Chemistry. 277: 4989-98
Kuryshev YA, Wible BA, Gudz TI, et al. (2001) KChAP/Kvbeta1.2 interactions and their effects on cardiac Kv channel expression. American Journal of Physiology. Cell Physiology. 281: C290-9
Ficker E, Dennis AT, Obejero-Paz CA, et al. (2000) Retention in the endoplasmic reticulum as a mechanism of dominant-negative current suppression in human long QT syndrome Journal of Molecular and Cellular Cardiology. 32: 2327-2337
Bianchi L, Priori SG, Napolitano C, et al. (2000) Mechanisms of I(Ks) suppression in LQT1 mutants. American Journal of Physiology. Heart and Circulatory Physiology. 279: H3003-11
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