Jeffrey S Flier

Affiliations: 
Medicine Harvard - BIDMC 
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"Jeffrey Flier"
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Flier JS, Ahima RS. (2024) Leptin physiology and pathophysiology: knowns and unknowns 30 years after its discovery. The Journal of Clinical Investigation. 134
Flier JS, Maratos-Flier E. (2017) Leptin's Physiologic Role: Does the Emperor of Energy Balance Have No Clothes? Cell Metabolism. 26: 24-26
Briancon N, McNay DE, Maratos-Flier E, et al. (2010) Combined neural inactivation of suppressor of cytokine signaling-3 and protein-tyrosine phosphatase-1B reveals additive, synergistic, and factor-specific roles in the regulation of body energy balance. Diabetes. 59: 3074-84
Zhang R, Maratos-Flier E, Flier JS. (2009) Reduced adiposity and high-fat diet-induced adipose inflammation in mice deficient for phosphodiesterase 4B. Endocrinology. 150: 3076-82
Shi H, Kokoeva MV, Inouye K, et al. (2006) TLR4 links innate immunity and fatty acid-induced insulin resistance. The Journal of Clinical Investigation. 116: 3015-25
Kievit P, Howard JK, Badman MK, et al. (2006) Enhanced leptin sensitivity and improved glucose homeostasis in mice lacking suppressor of cytokine signaling-3 in POMC-expressing cells. Cell Metabolism. 4: 123-32
Münzberg H, Flier JS, Bjørbaek C. (2004) Region-specific leptin resistance within the hypothalamus of diet-induced obese mice. Endocrinology. 145: 4880-9
Howard JK, Cave BJ, Oksanen LJ, et al. (2004) Enhanced leptin sensitivity and attenuation of diet-induced obesity in mice with haploinsufficiency of Socs3. Nature Medicine. 10: 734-8
Kelly JF, Elias CF, Lee CE, et al. (2004) Ciliary neurotrophic factor and leptin induce distinct patterns of immediate early gene expression in the brain. Diabetes. 53: 911-20
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