Fredrick G. Karnell, Ph.D.
Affiliations: | 2008 | University of Pennsylvania, Philadelphia, PA, United States |
Area:
Immunology, Cell BiologyGoogle:
"Fredrick Karnell"Mean distance: (not calculated yet)
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Sign in to add mentor| John G. Monroe | grad student | 2008 | Penn | |
| (Developmental-associated differences in membrane cholesterol content play a defining role in the response of transitional immature and mature B cells upon B cell receptor engagement.) | ||||
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Publications
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| Karnell JL, Dimasi N, Karnell FG, et al. (2014) CD19 and CD32b differentially regulate human B cell responsiveness. Journal of Immunology (Baltimore, Md. : 1950). 192: 1480-90 |
| Aster JC, Bodnar N, Xu L, et al. (2011) Notch ankyrin repeat domain variation influences leukemogenesis and Myc transactivation. Plos One. 6: e25645 |
| Karnell JL, Karnell FG, Stephens GL, et al. (2011) Mycophenolic acid differentially impacts B cell function depending on the stage of differentiation. Journal of Immunology (Baltimore, Md. : 1950). 187: 3603-12 |
| Stadanlick JE, Kaileh M, Karnell FG, et al. (2008) Tonic B cell antigen receptor signals supply an NF-kappaB substrate for prosurvival BLyS signaling. Nature Immunology. 9: 1379-87 |
| Fuentes-PananĂ¡ EM, Bannish G, Karnell FG, et al. (2006) Analysis of the individual contributions of Igalpha (CD79a)- and Igbeta (CD79b)-mediated tonic signaling for bone marrow B cell development and peripheral B cell maturation. Journal of Immunology (Baltimore, Md. : 1950). 177: 7913-22 |
| Zweidler-McKay PA, He Y, Xu L, et al. (2005) Notch signaling is a potent inducer of growth arrest and apoptosis in a wide range of B-cell malignancies. Blood. 106: 3898-906 |
| Karnell FG, Brezski RJ, King LB, et al. (2005) Membrane cholesterol content accounts for developmental differences in surface B cell receptor compartmentalization and signaling. The Journal of Biological Chemistry. 280: 25621-8 |
| He Y, Wertheim JA, Xu L, et al. (2002) The coiled-coil domain and Tyr177 of bcr are required to induce a murine chronic myelogenous leukemia-like disease by bcr/abl. Blood. 99: 2957-68 |
| Izon DJ, Aster JC, He Y, et al. (2002) Deltex1 redirects lymphoid progenitors to the B cell lineage by antagonizing Notch1. Immunity. 16: 231-43 |