Keith A. Wafford

Affiliations: 
Eli Lilly, Indianapolis, IN, United States 
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"Keith Wafford"
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Publications

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Wood CM, Nicolas CS, Choi SL, et al. (2016) Prevalence and influence of cys407* Grm2 mutation in Hannover-derived Wistar rats: mGlu2 receptor loss links to alcohol intake, risk taking and emotional behaviour. Neuropharmacology
Post A, Smart TS, Krikke-Workel J, et al. (2015) A Selective Nociceptin Receptor Antagonist to Treat Depression: Evidence from Preclinical and Clinical Studies. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology
Steinberg EA, Wafford KA, Brickley SG, et al. (2015) The role of K₂p channels in anaesthesia and sleep. PflüGers Archiv : European Journal of Physiology. 467: 907-16
Wodarski R, Schuh-Hofer S, Yurek DA, et al. (2015) Development and pharmacological characterization of a model of sleep disruption-induced hypersensitivity in the rat. European Journal of Pain (London, England). 19: 554-66
Jensen ML, Wafford KA, Brown AR, et al. (2013) A study of subunit selectivity, mechanism and site of action of the delta selective compound 2 (DS2) at human recombinant and rodent native GABA(A) receptors. British Journal of Pharmacology. 168: 1118-32
Gilmour G, Broad LM, Wafford KA, et al. (2013) In vitro characterisation of the novel positive allosteric modulators of the mGluâ‚… receptor, LSN2463359 and LSN2814617, and their effects on sleep architecture and operant responding in the rat. Neuropharmacology. 64: 224-39
Phillips KG, Bartsch U, McCarthy AP, et al. (2012) Decoupling of sleep-dependent cortical and hippocampal interactions in a neurodevelopmental model of schizophrenia. Neuron. 76: 526-33
Phillips KG, Cotel MC, McCarthy AP, et al. (2012) Differential effects of NMDA antagonists on high frequency and gamma EEG oscillations in a neurodevelopmental model of schizophrenia. Neuropharmacology. 62: 1359-70
Mirza NR, Atack J, Wafford K. (2012) GABA A receptor subtypes: Novel targets for novel medicines Advances in Pharmacological Sciences. 2012
Fell MJ, Witkin JM, Falcone JF, et al. (2011) N-(4-((2-(trifluoromethyl)-3-hydroxy-4-(isobutyryl)phenoxy)methyl)benzyl)-1-methyl-1H-imidazole-4-carboxamide (THIIC), a novel metabotropic glutamate 2 potentiator with potential anxiolytic/antidepressant properties: in vivo profiling suggests a link between behavioral and central nervous system neurochemical changes. The Journal of Pharmacology and Experimental Therapeutics. 336: 165-77
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