Zsofia Hegedus

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2016-2019 School of Chemistry University of Leeds (United Kingdom) 
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"Zsofia Hegedus"
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Petrovicz VL, Pasztuhov I, Martinek TA, et al. (2024) Site-directed allostery perturbation to probe the negative regulation of hypoxia inducible factor-1α. Rsc Chemical Biology. 5: 711-720
Tököli A, Bodnár B, Bogár F, et al. (2023) Structural Adaptation of the Single-Stranded DNA-Binding Protein C-Terminal to DNA Metabolizing Partners Guides Inhibitor Design. Pharmaceutics. 15
Srdanović S, Hegedüs Z, Warriner SL, et al. (2022) Towards identification of protein-protein interaction stabilizers inhibitory peptide-fragment hybrids using templated fragment ligation. Rsc Chemical Biology. 3: 546-550
Hóbor F, Hegedüs Z, Ibarra AA, et al. (2022) Understanding p300-transcription factor interactions using sequence variation and hybridization. Rsc Chemical Biology. 3: 592-603
Hegedüs Z, Hóbor F, Shoemark DK, et al. (2021) Identification of β-strand mediated protein-protein interaction inhibitors using ligand-directed fragment ligation. Chemical Science. 12: 2286-2293
Celis S, Hobor F, James T, et al. (2021) Query-guided protein-protein interaction inhibitor discovery. Chemical Science. 12: 4753-4762
Hetherington K, Hegedus Z, Edwards TA, et al. (2020) Stapled Peptides as HIF-1α/p300 Inhibitors: Helicity Enhancement in the Bound State Increases Inhibitory Potency. Chemistry (Weinheim An Der Bergstrasse, Germany)
Turalić A, Đeđibegović J, Hegedüs Z, et al. (2020) DPP-4 Cleaves α/β-Peptide Bonds: Substrate Specificity and Half-Lives. Chembiochem : a European Journal of Chemical Biology. 21: 2060-2066
Ibarra AA, Bartlett GJ, Hegedüs Z, et al. (2019) Predicting and Experimentally Validating Hot-spot Residues at Protein-Protein Interfaces. Acs Chemical Biology
Hegedus Z, Grison CM, Miles JA, et al. (2019) A catalytic protein-proteomimetic complex: using aromatic oligoamide foldamers as activators of RNase S. Chemical Science. 10: 3956-3962
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