Timothy J Hines, Ph.D.
Affiliations: | 2018- | The Jackson Laboratory, Bar Harbor, ME, United States |
Area:
Charcot-Marie-Tooth disease, peripheral neuropathy, axon degeneration, tRNA synthetases, genetics, neuromuscular diseaseGoogle:
"Timothy Hines"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Mark C. Zrull | research assistant | 2010-2012 | Appalachian State University | |
| (I worked in Dr. Zrull's lab as an undergraduate RA.) | ||||
| Deanna Sue Smith | grad student | 2012-2018 | University of South Carolina | |
| (I did my Ph.D. with Deanna studying the regulation of dynein-dependent axonal transport.) | ||||
| Robert Burgess | post-doc | 2018- | The Jackson Laboratory | |
| (Currently a postdoc in Rob's lab studying how mutations in tRNA synthetases cause motor neuron degeneration in Charcot-Marie-Tooth disease.) | ||||
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Publications
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| Martin PB, Holbrook SE, Hicks AN, et al. (2022) Clinically relevant mouse models of Charcot-Marie-Tooth Type 2S. Human Molecular Genetics |
| Hines TJ, Lutz C, Murray SA, et al. (2022) An Integrated Approach to Studying Rare Neuromuscular Diseases Using Animal and Human Cell-Based Models. Frontiers in Cell and Developmental Biology. 9: 801819 |
| Hines TJ, Tadenev ALD, Lone MA, et al. (2021) Precision mouse models of Yars/dominant intermediate Charcot-Marie-Tooth disease type C and Sptlc1/hereditary sensory and autonomic neuropathy type 1. Journal of Anatomy |
| Spaulding EL, Hines TJ, Bais P, et al. (2021) The integrated stress response contributes to tRNA synthetase–associated peripheral neuropathy Science. 373: 1156-1161 |
| Racine JJ, Chapman HD, Doty R, et al. (2020) T Cells from NOD- Mice Target Both Pancreatic and Neuronal Tissue. Journal of Immunology (Baltimore, Md. : 1950) |
| Morelli KH, Griffin LB, Pyne NK, et al. (2019) Allele-specific RNA interference prevents neuropathy in Charcot-Marie-Tooth disease type 2D mouse models. The Journal of Clinical Investigation |
| Shi L, Hines T, Bergson C, et al. (2018) Coupling of microtubule motors with AP-3 generated organelles in axons by NEEP21 Family Member Calcyon. Molecular Biology of the Cell. mbcE18010007 |
| Hines TJ, Gao X, Sahu S, et al. (2018) An Essential Postdevelopmental Role for Lis1 in Mice. Eneuro. 5 |
| Gao FJ, Shi L, Hines T, et al. (2017) Insulin signaling regulates a functional interaction between Adenomatous Polyposis Coli (APC) and cytoplasmic dynein. Molecular Biology of the Cell |
| Kalinski AL*, Hines TJ*, Smith DS, et al. (2015) Neuronal Transport and Spatial Signaling Mechanisms in Neural Repair Encyclopedia of Cell Biology. 3: 230-242 |