Timothy J Hines, Ph.D.

2018- The Jackson Laboratory, Bar Harbor, ME, United States 
Charcot-Marie-Tooth disease, peripheral neuropathy, axon degeneration, tRNA synthetases, genetics, neuromuscular disease
"Timothy Hines"
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Mark C. Zrull research assistant 2010-2012 Appalachian State University
 (I worked in Dr. Zrull's lab as an undergraduate RA.)
Deanna Sue Smith grad student 2012-2018 University of South Carolina
 (I did my Ph.D. with Deanna studying the regulation of dynein-dependent axonal transport.)
Robert Burgess post-doc 2018- The Jackson Laboratory
 (Currently a postdoc in Rob's lab studying how mutations in tRNA synthetases cause motor neuron degeneration in Charcot-Marie-Tooth disease.)
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Martin PB, Holbrook SE, Hicks AN, et al. (2022) Clinically relevant mouse models of Charcot-Marie-Tooth Type 2S. Human Molecular Genetics
Hines TJ, Lutz C, Murray SA, et al. (2022) An Integrated Approach to Studying Rare Neuromuscular Diseases Using Animal and Human Cell-Based Models. Frontiers in Cell and Developmental Biology. 9: 801819
Hines TJ, Tadenev ALD, Lone MA, et al. (2021) Precision mouse models of Yars/dominant intermediate Charcot-Marie-Tooth disease type C and Sptlc1/hereditary sensory and autonomic neuropathy type 1. Journal of Anatomy
Spaulding EL, Hines TJ, Bais P, et al. (2021) The integrated stress response contributes to tRNA synthetase–associated peripheral neuropathy Science. 373: 1156-1161
Racine JJ, Chapman HD, Doty R, et al. (2020) T Cells from NOD- Mice Target Both Pancreatic and Neuronal Tissue. Journal of Immunology (Baltimore, Md. : 1950)
Morelli KH, Griffin LB, Pyne NK, et al. (2019) Allele-specific RNA interference prevents neuropathy in Charcot-Marie-Tooth disease type 2D mouse models. The Journal of Clinical Investigation
Shi L, Hines T, Bergson C, et al. (2018) Coupling of microtubule motors with AP-3 generated organelles in axons by NEEP21 Family Member Calcyon. Molecular Biology of the Cell. mbcE18010007
Hines TJ, Gao X, Sahu S, et al. (2018) An Essential Postdevelopmental Role for Lis1 in Mice. Eneuro. 5
Gao FJ, Shi L, Hines T, et al. (2017) Insulin signaling regulates a functional interaction between Adenomatous Polyposis Coli (APC) and cytoplasmic dynein. Molecular Biology of the Cell
Kalinski AL*, Hines TJ*, Smith DS, et al. (2015) Neuronal Transport and Spatial Signaling Mechanisms in Neural Repair Encyclopedia of Cell Biology. 3: 230-242
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