Paul J Shim

Affiliations: 
Duke University, Durham, NC 
Area:
GPCR, Arrestins
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"Paul Shim"
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Publications

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Lefkowitz RJ, Rockman HA, Shim PJ, et al. (2023) How carvedilol does not activate β-adrenoceptors. Nature Communications. 14: 7866
Kahsai AW, Shah KS, Shim PJ, et al. (2023) Signal transduction at GPCRs: Allosteric activation of the ERK MAPK by β-arrestin. Proceedings of the National Academy of Sciences of the United States of America. 120: e2303794120
Liu X, Masoudi A, Kahsai AW, et al. (2019) Mechanism of βAR regulation by an intracellular positive allosteric modulator. Science (New York, N.Y.). 364: 1283-1287
Ahn S, Pani B, Kahsai AW, et al. (2018) Small Molecule Positive Allosteric Modulators of the β-Adrenoceptor Isolated from DNA Encoded Libraries. Molecular Pharmacology
Meng K, Shim P, Wang Q, et al. (2018) Design, synthesis, and functional assessment of Cmpd-15 derivatives as negative allosteric modulators for the β-adrenergic receptor. Bioorganic & Medicinal Chemistry
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