Mark A Lewis
Affiliations: | 2003-2007 | Chemistry & Chemical Biology | Indiana University-Indianapolis |
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| Goodwin KD, Lewis MA, Long EC, et al. (2022) Two distinct rotations of bithiazole DNA intercalation revealed by direct comparison of crystal structures of Co(III)•bleomycin A and B bound to duplex 5'-TAGTT sites. Bioorganic & Medicinal Chemistry. 77: 117113 |
| Opperman TJ, Kwasny SM, Li JB, et al. (2016) DNA Targeting as a Likely Mechanism Underlying the Antibacterial Activity of Synthetic Bis-indole Antibiotics. Antimicrobial Agents and Chemotherapy |
| Lewis MA, Williams KM, Fang YY, et al. (2014) DNA Cleaving "Tandem-Array" Metallopeptides Activated With KHSO5: Towards the Development of Multi-Metallated Bioactive Conjugates and Compounds. Current Bioactive Compounds. 10: 13-20 |
| Goodwin KD, Lewis MA, Long EC, et al. (2008) Crystal structure of DNA-bound Co(III) bleomycin B2: Insights on intercalation and minor groove binding. Proceedings of the National Academy of Sciences of the United States of America. 105: 5052-6 |
| Hamada H, Abe Y, Nagane R, et al. (2007) DNA-fiber EPR investigation of the influence of amino-terminal residue stereochemistry on the DNA binding orientation of Cu(II).Gly-Gly-His-derived metallopeptides. Journal of Inorganic Biochemistry. 101: 1529-36 |
| Jin Y, Lewis MA, Gokhale NH, et al. (2007) Influence of stereochemistry and redox potentials on the single- and double-strand DNA cleavage efficiency of Cu(II) and Ni(II) Lys-Gly-His-derived ATCUN metallopeptides. Journal of the American Chemical Society. 129: 8353-61 |
| Tanious FA, Laine W, Peixoto P, et al. (2007) Unusually strong binding to the DNA minor groove by a highly twisted benzimidazole diphenylether: induced fit and bound water. Biochemistry. 46: 6944-56 |
| Goodwin KD, Lewis MA, Tanious FA, et al. (2006) A high-throughput, high-resolution strategy for the study of site-selective DNA binding agents: analysis of a "highly twisted" benzimidazole-diamidine. Journal of the American Chemical Society. 128: 7846-54 |
| Lewis MA, Long EC. (2006) Fluorescent intercalator displacement analyses of DNA binding by the peptide-derived natural products netropsin, actinomycin, and bleomycin. Bioorganic & Medicinal Chemistry. 14: 3481-90 |