Lena Afeyan

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Biology Massachusetts Institute of Technology, Cambridge, MA, United States 
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"Lena Afeyan"
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Richard A. Young grad student 2019-2022 MIT
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Banani SF, Afeyan LK, Hawken SW, et al. (2022) Genetic variation associated with condensate dysregulation in disease. Developmental Cell
Chaves-Moreira D, Mitchell MA, Arruza C, et al. (2022) The transcription factor PAX8 promotes angiogenesis in ovarian cancer through interaction with SOX17. Science Signaling. 15: eabm2496
Reddy J, Fonseca MAS, Corona RI, et al. (2021) Predicting master transcription factors from pan-cancer expression data. Science Advances. 7: eabf6123
Li CH, Coffey EL, Dall'Agnese A, et al. (2020) MeCP2 links heterochromatin condensates and neurodevelopmental disease. Nature
Klein IA, Boija A, Afeyan LK, et al. (2020) Partitioning of cancer therapeutics in nuclear condensates. Science (New York, N.Y.). 368: 1386-1392
Zamudio AV, Dall'Agnese A, Henninger JE, et al. (2019) Mediator Condensates Localize Signaling Factors to Key Cell Identity Genes. Molecular Cell
Guo YE, Manteiga JC, Henninger JE, et al. (2019) Pol II phosphorylation regulates a switch between transcriptional and splicing condensates. Nature
Boija A, Klein IA, Sabari BR, et al. (2018) Transcription Factors Activate Genes through the Phase-Separation Capacity of Their Activation Domains. Cell
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