Jan Wijnholds
Affiliations: | Netherlands Institute for Neuroscience, Amsterdam-Zuidoost, Noord-Holland, Netherlands |
Area:
retinal degenerationWebsite:
http://www.nin.knaw.nl/research_groups/wijnholds_group/jan_wijnholdsGoogle:
"Jan Wijnholds"Bio:
http://alba.ub.rug.nl/promotorum/?page=showPerson&promovendus_id=4216&lang=nl
Mean distance: 24.73 | S | N | B | C | P |
Parents
Sign in to add mentor| Jaap J. Beintema | grad student | 1991 | RUG (Chemistry Tree) | |
| (Liver-specific regulation of the oestrogen-inducible apoVLDLII gene) | ||||
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Publications
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| McDonald A, Wijnholds J. (2024) Retinal Ciliopathies and Potential Gene Therapies: A Focus on Human iPSC-Derived Organoid Models. International Journal of Molecular Sciences. 25 |
| Boon N, Lu X, Andriessen CA, et al. (2023) Characterization and AAV-mediated gene augmentation in human-derived and retinal organoids. Molecular Therapy. Methods & Clinical Development. 31: 101128 |
| Buck TM, Quinn PMJ, Pellissier LP, et al. (2023) CRB1 is required for recycling by RAB11A+ vesicles in human retinal organoids. Stem Cell Reports |
| Boon N, Lu X, Andriessen CA, et al. (2023) AAV-mediated gene augmentation therapy of CRB1 patient-derived retinal organoids restores the histological and transcriptional retinal phenotype. Stem Cell Reports. 18: 1388 |
| Boon N, Lu X, Andriessen CA, et al. (2023) AAV-mediated gene augmentation therapy of CRB1 patient-derived retinal organoids restores the histological and transcriptional retinal phenotype. Stem Cell Reports. 18: 1123-1137 |
| Boon N, Alves CH, Mulder AA, et al. (2021) Defining Phenotype, Tropism, and Retinal Gene Therapy Using Adeno-Associated Viral Vectors (AAVs) in New-Born Brown Norway Rats with a Spontaneous Mutation in . International Journal of Molecular Sciences. 22 |
| Buck TM, Vos RM, Alves CH, et al. (2021) AAV- protects against vision loss in an inducible retinitis pigmentosa mouse model. Molecular Therapy. Methods & Clinical Development. 20: 423-441 |
| Gallego C, Gonçalves MAFV, Wijnholds J. (2020) Novel Therapeutic Approaches for the Treatment of Retinal Degenerative Diseases: Focus on CRISPR/Cas-Based Gene Editing. Frontiers in Neuroscience. 14: 838 |
| Boon N, Wijnholds J, Pellissier LP. (2020) Research Models and Gene Augmentation Therapy for Retinal Dystrophies. Frontiers in Neuroscience. 14: 860 |
| Buck TM, Wijnholds J. (2020) Recombinant Adeno-Associated Viral Vectors (rAAV)-Vector Elements in Ocular Gene Therapy Clinical Trials and Transgene Expression and Bioactivity Assays. International Journal of Molecular Sciences. 21 |