Thomas J. Younts, Ph.D.

Affiliations: 
Neuroscience, Physiology and Pharmacology University College London, London, United Kingdom 
Area:
synapse, dendrite, plasticity, integration, signaling, networks, hippocampus, cortex
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"Thomas Younts"
Mean distance: 14.4 (cluster 11)
 
SNBCP

Parents

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Pablo Castillo grad student 2007-2014 Yeshiva University
 (Presynaptic forms of long-term plasticity in the mammalian hippocampus.)
Angus Silver post-doc 2015- UCL
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Publications

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Klein ME, Younts TJ, Cobo CF, et al. (2019) Sam68 Enables Metabotropic Glutamate Receptor-Dependent LTD in Distal Dendritic Regions of CA1 Hippocampal Neurons. Cell Reports. 29: 1789-1799.e6
Monday HR, Younts TJ, Castillo PE. (2018) Long-Term Plasticity of Neurotransmitter Release: Emerging Mechanisms and Contributions to Brain Function and Disease. Annual Review of Neuroscience
Jones BW, Deem J, Younts TJ, et al. (2016) Targeted deletion of AKAP7 in dentate granule cells impairs spatial discrimination. Elife. 5
Younts TJ, Monday HR, Dudok B, et al. (2016) Presynaptic Protein Synthesis Is Required for Long-Term Plasticity of GABA Release. Neuron. 92: 479-492
Younts TJ, Castillo PE. (2014) Endogenous cannabinoid signaling at inhibitory interneurons. Current Opinion in Neurobiology. 26: 42-50
Younts TJ, Chevaleyre V, Castillo PE. (2013) CA1 pyramidal cell theta-burst firing triggers endocannabinoid-mediated long-term depression at both somatic and dendritic inhibitory synapses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 13743-57
Kaeser-Woo YJ, Younts TJ, Yang X, et al. (2013) Synaptotagmin-12 phosphorylation by cAMP-dependent protein kinase is essential for hippocampal mossy fiber LTP. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 9769-80
Klein ME, Younts TJ, Castillo PE, et al. (2013) RNA-binding protein Sam68 controls synapse number and local β-actin mRNA metabolism in dendrites. Proceedings of the National Academy of Sciences of the United States of America. 110: 3125-30
Castillo PE, Younts TJ, Chávez AE, et al. (2012) Endocannabinoid signaling and synaptic function. Neuron. 76: 70-81
Tsetsenis T, Younts TJ, Chiu CQ, et al. (2011) Rab3B protein is required for long-term depression of hippocampal inhibitory synapses and for normal reversal learning. Proceedings of the National Academy of Sciences of the United States of America. 108: 14300-5
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