Frank LaFerla, Ph.D.

Affiliations: 
Neurobiology & Behavior University of California, Irvine, Irvine, CA 
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"Frank LaFerla"
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Stephen T. Yeung research assistant UC Irvine (ImmunoTree)
Meredith Chabrier (Reichert) grad student UC Irvine
Malcolm A. Leissring grad student 2000 UC Irvine
Yama Akbari grad student 2005 UC Irvine
Salvatore Oddo grad student 2005 UC Irvine
Bertrand P. Tseng grad student 2006 UC Irvine
Lani K. Clinton grad student 2007 UC Irvine
Tritia R. Yamasaki grad student 2007 UC Irvine
Debbi A. Morrissette grad student 2009 UC Irvine
Michael Sy grad student 2010 UC Irvine
Kara Neely grad student 2011 UC Irvine
Kristoffer Myczek grad student 2012 UC Irvine
Kristoffer Myczek grad student 2012 UC Irvine
Nicholas A. Castello grad student 2013 UC Irvine
Nicholas A. Castello grad student 2013 UC Irvine
Meredith Chabrier grad student 2013 UC Irvine
Mathew M. Blurton-Jones post-doc UC Irvine
Kim Green post-doc UC Irvine
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Publications

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Soni N, Hohsfield LA, Tran KM, et al. (2024) Genetic diversity promotes resilience in a mouse model of Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association
Terron HM, Parikh SJ, Abdul-Hay SO, et al. (2023) Prominent tauopathy and intracellular β-amyloid accumulation triggered by genetic deletion of cathepsin D: Implications for Alzheimer disease pathogenesis. Research Square
Terron HM, Maranan DS, Burgard LA, et al. (2023) A Dual-Function "TRE-Lox" System for Genetic Deletion or Reversible, Titratable, and Near-Complete Downregulation of Cathepsin D. International Journal of Molecular Sciences. 24
Tran KM, Kawauchi S, Kramár EA, et al. (2023) A Trem2 mouse model without cryptic splicing drives age- and disease-dependent tissue damage and synaptic loss in response to plaques. Molecular Neurodegeneration. 18: 12
Jong Huat T, Onraet T, Camats-Perna J, et al. (2022) Deletion of MyD88 in astrocytes prevents β-amyloid-induced neuropathology in mice. Glia
Javonillo DI, Tran KM, Phan J, et al. (2022) Systematic Phenotyping and Characterization of the 3xTg-AD Mouse Model of Alzheimer's Disease. Frontiers in Neuroscience. 15: 785276
Lin X, Chen L, Baglietto-Vargas D, et al. (2021) Spatial coding defects of hippocampal neural ensemble calcium activities in the triple-transgenic Alzheimer's disease mouse model. Neurobiology of Disease. 162: 105562
Trujillo-Estrada L, Vanderklish PW, Nguyen MMT, et al. (2021) SPG302 Reverses Synaptic and Cognitive Deficits Without Altering Amyloid or Tau Pathology in a Transgenic Model of Alzheimer's Disease. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics
Forner S, Kawauchi S, Balderrama-Gutierrez G, et al. (2021) Systematic phenotyping and characterization of the 5xFAD mouse model of Alzheimer's disease. Scientific Data. 8: 270
Baglietto-Vargas D, Forner S, Cai L, et al. (2021) Generation of a humanized Aβ expressing mouse demonstrating aspects of Alzheimer's disease-like pathology. Nature Communications. 12: 2421
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