Frank Sicheri
Affiliations: | Biochemistry | University of Toronto, Toronto, ON, Canada |
Area:
protein kinase regulationWebsite:
http://biochemistry.utoronto.ca/person/frank-sicheri/Google:
"Frank Sicheri"Bio:
http://www.mshri.on.ca/sicheri/
Mean distance: 8.36 | S | N | B | C | P |
Parents
Sign in to add mentorDaniel S.-C. Yang | grad student | 1989-1995 | McMaster University | |
(Ice binding structure and mechanism of an antifreeze protein from winter flounder) | ||||
John Kuriyan | post-doc | 1995-1997 | Rockefeller |
Children
Sign in to add traineeArvin C. Dar | grad student | 2006 | University of Toronto |
Yang-Chieh Chou | grad student | 2011 | University of Toronto |
Thanashan Rajakulendran | grad student | 2011 | University of Toronto |
Dante Neculai | post-doc | 2008-2011 | Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital (ImmunoTree) |
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Publications
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Maisonneuve P, Sahmi M, Bergeron-Labrecque F, et al. (2024) The CNK-HYP scaffolding complex promotes RAF activation by enhancing KSR-MEK interaction. Nature Structural & Molecular Biology |
Tessier TM, Chowdhury A, Stekel Z, et al. (2023) Structural and functional validation of a highly specific Smurf2 inhibitor. Protein Science : a Publication of the Protein Society. e4885 |
Kelso S, O'Brien S, Kurinov I, et al. (2022) Crystal structure of the CDK11 kinase domain bound to the small-molecule inhibitor OTS964. Structure (London, England : 1993). 30: 1615-1625.e4 |
Beenstock J, Ona SM, Sicheri F. (2022) A suite of in vitro and in vivo assays for monitoring the activity of the pseudokinase Bud32. Methods in Enzymology. 667: 729-773 |
Veggiani G, Yates BP, Martyn GD, et al. (2022) Panel of Engineered Ubiquitin Variants Targeting the Family of Human Ubiquitin Interacting Motifs. Acs Chemical Biology. 17: 941-956 |
Beenstock J, Sicheri F. (2021) The structural and functional workings of KEOPS. Nucleic Acids Research. 49: 10818-10834 |
Tavernier N, Sicheri F, Pintard L. (2021) Aurora A kinase activation: Different means to different ends. The Journal of Cell Biology. 220 |
Teyra J, McLaughlin M, Singer A, et al. (2021) Comprehensive Assessment of The Relationship Between Site Specificity and Helix α2 in the Erbin PDZ Domain. Journal of Molecular Biology. 167115 |
Kelso S, Orlicky S, Beenstock J, et al. (2021) Bipartite binding of the N terminus of Skp2 to cyclin A. Structure (London, England : 1993) |
Daou S, Talukdar M, Tang J, et al. (2020) A phenolic small molecule inhibitor of RNase L prevents cell death from ADAR1 deficiency. Proceedings of the National Academy of Sciences of the United States of America |