Jules A. Hoffmann

Affiliations: 
Université de Strasbourg 
Area:
Immunity
Website:
http://www.nobelprize.org/nobel_prizes/medicine/laureates/2011/hoffmann-facts.html
Google:
"Jules A. Hoffmann"
Bio:

The Nobel Prize in Physiology or Medicine 2011 was divided, one half jointly to Bruce A. Beutler and Jules A. Hoffmann for their discoveries concerning the activation of innate immunity and the other half to Ralph M. Steinman for his discovery of the dendritic cell and its role in adaptive immunity.

Cross-listing: ImmunoTree

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Publications

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Huang J, Lou Y, Liu J, et al. (2023) A Toll pathway effector protects specifically from distinct toxins secreted by a fungus or a bacterium. Proceedings of the National Academy of Sciences of the United States of America. 120: e2205140120
Goto A, Okado K, Martins N, et al. (2018) The Kinase IKKβ Regulates a STING- and NF-κB-Dependent Antiviral Response Pathway in Drosophila. Immunity
Lamiable O, Arnold J, da Silva de Faria IJ, et al. (2016) Analysis of the contribution of hemocytes and autophagy to Drosophila antiviral immunity. Journal of Virology
Lamiable O, Kellenberger C, Kemp C, et al. (2016) Cytokine Diedel and a viral homologue suppress the IMD pathway in Drosophila. Proceedings of the National Academy of Sciences of the United States of America
Majzoub K, Hafirassou ML, Meignin C, et al. (2014) RACK1 controls IRES-mediated translation of viruses. Cell. 159: 1086-95
Chtarbanova S, Lamiable O, Lee KZ, et al. (2014) Drosophila C virus systemic infection leads to intestinal obstruction. Journal of Virology. 88: 14057-69
Tartey S, Matsushita K, Vandenbon A, et al. (2014) Akirin2 is critical for inducing inflammatory genes by bridging IκB-ζ and the SWI/SNF complex. The Embo Journal. 33: 2332-48
Goto A, Fukuyama H, Imler JL, et al. (2014) The chromatin regulator DMAP1 modulates activity of the nuclear factor κB (NF-κB) transcription factor Relish in the Drosophila innate immune response Journal of Biological Chemistry. 289: 20470-20476
Fukuyama H, Verdier Y, Guan Y, et al. (2013) Landscape of protein-protein interactions in Drosophila immune deficiency signaling during bacterial challenge. Proceedings of the National Academy of Sciences of the United States of America. 110: 10717-22
Bonnay F, Cohen-Berros E, Hoffmann M, et al. (2013) big bang gene modulates gut immune tolerance in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 110: 2957-62
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