Daniel Ciulla
Affiliations: | National Center for Advancing Translational Sciences |
Area:
Enzymology, assay development, high throughput screeningGoogle:
"Daniel Ciulla"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Brian P. Callahan | grad student | 2018-2022 | SUNY Binghamton (Chemistry Tree) | |
| (Research advisor and mentor) | ||||
| James Inglese | post-doc | 2022- | ||
| (Research advisor and mentor) | ||||
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Publications
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| Ciulla DA, Xu Z, Pezzullo JL, et al. (2023) Paracatalytic induction: Subverting specificity in hedgehog protein autoprocessing with small molecules. Methods in Enzymology. 685: 1-41 |
| Ciulla DA, Dranchak P, Pezzullo JL, et al. (2022) A cell-based bioluminescence reporter assay of human Sonic Hedgehog protein autoprocessing to identify inhibitors and activators. The Journal of Biological Chemistry. 102705 |
| Callahan BP, Ciulla DA, Wagner AG, et al. (2020) Specificity Distorted: Chemical Induction of Biological Paracatalysis. Biochemistry |
| Zhao J, Ciulla DA, Xie J, et al. (2019) General Base Swap Preserves Activity and Expands Substrate Tolerance in Hedgehog Autoprocessing. Journal of the American Chemical Society |
| Zhang X, Xu Z, Moumin DS, et al. (2019) Protein-Nucleic Acid Conjugation with Sterol Linkers Using Hedgehog Autoprocessing. Bioconjugate Chemistry |
| Ciulla DA, Wagner AG, Liu X, et al. (2019) Sterol A-ring plasticity in hedgehog protein cholesterolysis supports a primitive substrate selectivity mechanism. Chemical Communications (Cambridge, England) |
| Ciulla D, Jorgensen M, Giner JL, et al. (2017) Chemical bypass of general base catalysis in hedgehog protein cholesterolysis using a hyper-nucleophilic substrate. Journal of the American Chemical Society |
| Bordeau BM, Ciulla DA, Callahan BP. (2016) Hedgehog Proteins Consume Steroidal CYP17A1 Antagonists: Potential Therapeutic Significance in Advanced Prostate Cancer. Chemmedchem |