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Brendan Patrick Orner, Ph.D., M.S., B.S.

Affiliations: 
2006-2012 Chemistry and Biological Chemistry Nanyang Technological University, Singapore, Singapore 
 2012- none Unemployed, Harlingen, TX, United States 
 2012-2016 Chemistry King's College London, London, UK 
Area:
Directed Evolution, Phage Display, Protein Engineering, Molecular Biology, Chemical Biology, Synthetic Biology, Medicinal Chemistry, Protein Chemistry, Organic Chemistry, Nanomaterials
Website:
http://orner-lab.appspot.com/
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"Brendan Orner"
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Parents

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Andrew D. Hamilton grad student 2001 Yale
 (Molecular recognition of protein surfaces involving the alpha-Helix: A molecular design approach.)
Andrew D. Hamilton grad student 2001 Yale
 (Molecular recognition of protein surfaces involving the alpha-Helix: A molecular design approach.)
Laura Lee Kiessling post-doc 2001-2006

Children

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Maziar S. Ardejani grad student King's College
Tom Cornell grad student King's College
Rongli Fan grad student Nanyang Technological University
Yu Zhang grad student Nanyang Technological University

Collaborators

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Publications

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Cornell TA, Orner BP. (2018) Medium throughput cage state stability screen of conditions for the generation of gold nanoparticles encapsulated within a mini-ferritin. Bioorganic & Medicinal Chemistry. 26: 5253-5258
Zhang Y, Zhou J, Ardejani MS, et al. (2017) Designability of Aromatic Interaction Networks at E. coli Bacterioferritin B-Type Channels. Molecules (Basel, Switzerland). 22
Cornell T, Ardejani MS, Fu J, et al. (2017) A Structure-Based Assembly Screen of Protein Cage Libraries in Living Cells: Experimentally Repacking a Protein-Protein Interface to Recover Cage Formation in an Assembly-Frustrated Mutant. Biochemistry
Cornell T, Srivastava Y, Jauch R, et al. (2017) The Crystal Structure of a Maxi-/Mini-Ferritin Chimera Reveals Guiding Principles for the Assembly of Protein Cages. Biochemistry
Hui Hiew S, Guerette PA, Zvarec OJ, et al. (2016) Modular peptides from the thermoplastic squid sucker ring teeth form amyloid-like cross-βsupramolecular networks. Acta Biomaterialia
Zhang Y, Ardejani MS, Orner BP. (2016) Design and applications of protein cage-based nanomaterials. Chemistry, An Asian Journal
Zhang Y, Wang L, Ardejani MS, et al. (2015) Mutagenesis Study to Disrupt Electrostatic Interactions on the Two-fold Symmetry Interface of E. coli Bacterioferritin. Journal of Biochemistry
Cornell TA, Orner BP. (2015) Detection of protein cage assembly with bisarsenic fluorescent probes Methods in Molecular Biology. 1252: 79-89
Ardejani MS, Orner BP. (2015) Computationally assisted engineering of protein cages Methods in Molecular Biology. 1252: 51-59
Cornell TA, Fu J, Newland SH, et al. (2013) Detection of specific protein-protein interactions in nanocages by engineering bipartite FlAsH binding sites Journal of the American Chemical Society. 135: 16618-16624
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