J David Spafford

Biology University of Waterloo, Waterloo, ON, Canada 
"J Spafford"
Mean distance: 17.95 (cluster 11)
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Chemin J, Taiakina V, Monteil A, et al. (2017) Calmodulin regulates Cav3 T-type channels at their gating brake. The Journal of Biological Chemistry
Casillas-Espinosa PM, Hicks A, Jeffreys A, et al. (2015) Z944, a Novel Selective T-Type Calcium Channel Antagonist Delays the Progression of Seizures in the Amygdala Kindling Model. Plos One. 10: e0130012
Stephens RF, Guan W, Zhorov BS, et al. (2015) Selectivity filters and cysteine-rich extracellular loops in voltage-gated sodium, calcium, and NALCN channels. Frontiers in Physiology. 6: 153
Senatore A, Spafford JD. (2015) Physiology and pathology of voltage-gated t-type calcium channels T-Type Calcium Channels in Basic and Clinical Science. 3-17
Boone AN, Senatore A, Chemin J, et al. (2014) Gd3+ and calcium sensitive, sodium leak currents are features of weak membrane-glass seals in patch clamp recordings. Plos One. 9: e98808
Dawson TF, Boone AN, Senatore A, et al. (2014) Gene splicing of an invertebrate beta subunit (LCavβ) in the N-terminal and HOOK domains and its regulation of LCav1 and LCav2 calcium channels. Plos One. 9: e92941
Senatore A, Guan W, Boone AN, et al. (2014) T-type channels become highly permeable to sodium ions using an alternative extracellular turret region (S5-P) outside the selectivity filter. The Journal of Biological Chemistry. 289: 11952-69
Senatore A, Guan W, Spafford JD. (2014) Cav3 T-type channels: regulators for gating, membrane expression, and cation selectivity. PflüGers Archiv : European Journal of Physiology. 466: 645-60
Guan W, Stephens RF, Spafford JD. (2014) Cav3 T-type channels as drug targets for treating epilepsy Future Neurology. 9: 563-566
Taiakina V, Boone AN, Fux J, et al. (2014) Correction: The calmodulin-binding, short linear motif, NSCaTE is conserved in L-type channel ancestors of vertebrate Cav1.2 and Cav1.3 channels (PLoS ONE) Plos One. 9
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