Sergei Y. Noskov, Ph.D.

Affiliations: 
Biochemistry University of Calgary, Calgary, Alberta, Canada 
Area:
computational chemistry, ion channels, statistical thermodynamics
Website:
http://www.noskovlab.com/
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"Sergei Noskov"
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Publications

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Kudaibergenova M, Guo J, Khan HM, et al. (2022) The voltage-sensing domain of a hERG1 mutant is a cation-selective channel. Biophysical Journal. 121: 4585-4599
Ngo VA, Queralt-Martín M, Khan F, et al. (2022) The Single Residue K12 Governs the Exceptional Voltage Sensitivity of Mitochondrial Voltage-Dependent Anion Channel Gating. Journal of the American Chemical Society. 144: 14564-14577
Zhekova HR, Wang W, Tsirulnikov K, et al. (2022) Insights Into the Na -Dependent Anion Exchange in the SLC4 Family From the Cryo-EM Structure of the Sodium-Driven Chloride/Bicarbonate Exchanger SLC4A8. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology
Corradi V, Bukiya AN, Miranda WE, et al. (2022) A molecular switch controls the impact of cholesterol on a Kir channel. Proceedings of the National Academy of Sciences of the United States of America. 119: e2109431119
Wu X, Ramentol R, Perez ME, et al. (2021) A second S4 movement opens hyperpolarization-activated HCN channels. Proceedings of the National Academy of Sciences of the United States of America. 118
Yazdi S, Nikesjö J, Miranda W, et al. (2021) Identification of PUFA interaction sites on the cardiac potassium channel KCNQ1. The Journal of General Physiology. 153
Miranda WE, Guo J, Mesa-Galloso H, et al. (2021) Lipid regulation of hERG1 channel function. Nature Communications. 12: 1409
Ngo V, Li H, MacKerell AD, et al. (2021) Polarization Effects in Water-Mediated Selective Cation Transport across a Narrow Transmembrane Channel. Journal of Chemical Theory and Computation
Mousaei M, Kudaibergenova M, MacKerell AD, et al. (2020) Assessing hERG1 Blockade from Bayesian Machine-Learning-Optimized Site Identification by Ligand Competitive Saturation Simulations. Journal of Chemical Information and Modeling. 60: 6489-6501
Kudaibergenova M, Guo J, Khan HM, et al. (2020) Allosteric Coupling Between Drug Binding and the Aromatic Cassette in the Pore Domain of the hERG1 Channel: Implications for a State-Dependent Blockade. Frontiers in Pharmacology. 11: 914
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