Alberto Pascual, Ph.D.

Affiliations: 
2007- Instituto de Biomedicina de Sevilla, IBiS (CSIC) 
Area:
Neuroscience, microglia, non-neuronal cells, brain metabolism
Website:
https://www.ibis-sevilla.es/en/research/neurosciences/mechanisms-of-neuronal-maintenance/
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"Alberto Pascual"
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Parents

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Jose Lopez-Barneo research assistant 2003-2007
Agustin Vioque grad student 1995-1998 IBVF, CSIC, Seville
Thomas Preat post-doc 1999-2002
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Publications

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Moreno-Domínguez A, Colinas O, Arias-Mayenco I, et al. (2024) Hif1α-dependent mitochondrial acute O sensing and signaling to myocyte Ca channels mediate arterial hypoxic vasodilation. Nature Communications. 15: 6649
Mora-Romero B, Capelo-Carrasco N, Pérez-Moreno JJ, et al. (2024) Microglia mitochondrial complex I deficiency during development induces glial dysfunction and early lethality. Nature Metabolism
Villadiego J, García-Arriaza J, Ramírez-Lorca R, et al. (2023) Full protection from SARS-CoV-2 brain infection and damage in susceptible transgenic mice conferred by MVA-CoV2-S vaccine candidate. Nature Neuroscience. 26: 226-238
Silva B, Mantha OL, Schor J, et al. (2022) Glia fuel neurons with locally synthesized ketone bodies to sustain memory under starvation. Nature Metabolism
March-Diaz R, Lara-Ureña N, Romero-Molina C, et al. (2021) Hypoxia compromises the mitochondrial metabolism of Alzheimer's disease microglia via HIF1. Nature Aging. 1: 385-399
Harasztosi C, Wolter S, Gutsche K, et al. (2019) Differential deletion of GDNF in the auditory system leads to altered sound responsiveness. Journal of Neuroscience Research
Dong C, Helton ES, Zhou P, et al. (2018) Glial-derived neurotrophic factor is essential for blood-nerve barrier functional recovery in an experimental murine model of traumatic peripheral neuropathy. Tissue Barriers. 1-48
Serrano-Pozo A, Sánchez-García MA, Heras-Garvín A, et al. (2017) Acute and Chronic Sustained Hypoxia Do Not Substantially Regulate Amyloid-β Peptide Generation In Vivo. Plos One. 12: e0170345
Fernández-Agüera MC, Gao L, González-Rodríguez P, et al. (2015) Oxygen Sensing by Arterial Chemoreceptors Depends on Mitochondrial Complex I Signaling. Cell Metabolism
d'Anglemont de Tassigny X, Pascual A, López-Barneo J. (2015) GDNF-based therapies, GDNF-producing interneurons, and trophic support of the dopaminergic nigrostriatal pathway. Implications for Parkinson's disease. Frontiers in Neuroanatomy. 9: 10
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