Shan Chen

Steven A. Siegelbaum	grad student	2002	Columbia
(Structure, gating and modulation of hyperpolarization -activated HCN pacemaker channels.)

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Pan Y, Guo X, Yang Z, et al. (2015) AEG-1 activates Wnt/PCP signaling to promote metastasis in tongue squamous cell carcinoma. Oncotarget
Chen S, Wang J, Zhou L, et al. (2007) Voltage sensor movement and cAMP binding allosterically regulate an inherently voltage-independent closed-open transition in HCN channels. The Journal of General Physiology. 129: 175-88
Wang J, Chen S, Nolan MF, et al. (2002) Activity-dependent regulation of HCN pacemaker channels by cyclic AMP: signaling through dynamic allosteric coupling. Neuron. 36: 451-61
Wang J, Chen S, Siegelbaum SA. (2001) Regulation of hyperpolarization-activated HCN channel gating and cAMP modulation due to interactions of COOH terminus and core transmembrane regions. The Journal of General Physiology. 118: 237-50
Chen S, Wang J, Siegelbaum SA. (2001) Properties of hyperpolarization-activated pacemaker current defined by coassembly of HCN1 and HCN2 subunits and basal modulation by cyclic nucleotide. The Journal of General Physiology. 117: 491-504
Santoro B, Chen S, Luthi A, et al. (2000) Molecular and functional heterogeneity of hyperpolarization-activated pacemaker channels in the mouse CNS. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 5264-75