Andrew Mark Swensen

Affiliations: 
2000 Brandeis University, Waltham, MA, United States 
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"Andrew Swensen"
Mean distance: 14.46 (cluster 6)
 
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Eve Marder grad student 2000 Brandeis
 (Network consequences of convergent modulation in the stomatogastric nervous system of the crab, Cancer borealis.)
Steve McGaraughty research scientist AbbVie Labs
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Publications

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Swensen AM, Niforatos W, Lee CH, et al. (2014) Characterization of the triazine, T4, a representative from a novel series of CaV2 inhibitors with strong state-dependence, poor use-dependence, and distinctively fast kinetics. European Journal of Pharmacology. 745: 234-42
Zhu CZ, Vortherms TA, Zhang M, et al. (2014) Mechanistic insights into the analgesic efficacy of A-1264087, a novel neuronal Ca(2+) channel blocker that reduces nociception in rat preclinical pain models. The Journal of Pain : Official Journal of the American Pain Society. 15: 387.e1-14
Xu J, Chu KL, Zhu CZ, et al. (2014) A mixed Ca2+ channel blocker, A-1264087, utilizes peripheral and spinal mechanisms to inhibit spinal nociceptive transmission in a rat model of neuropathic pain. Journal of Neurophysiology. 111: 394-404
Swensen AM, Niforatos W, Vortherms TA, et al. (2012) An automated electrophysiological assay for differentiating Ca(v)2.2 inhibitors based on state dependence and kinetics. Assay and Drug Development Technologies. 10: 542-50
Scott VE, Vortherms TA, Niforatos W, et al. (2012) A-1048400 is a novel, orally active, state-dependent neuronal calcium channel blocker that produces dose-dependent antinociception without altering hemodynamic function in rats. Biochemical Pharmacology. 83: 406-18
Abbadie C, McManus OB, Sun SY, et al. (2010) Analgesic effects of a substituted N-triazole oxindole (TROX-1), a state-dependent, voltage-gated calcium channel 2 blocker. The Journal of Pharmacology and Experimental Therapeutics. 334: 545-55
Dai G, Haedo RJ, Warren VA, et al. (2008) A high-throughput assay for evaluating state dependence and subtype selectivity of Cav2 calcium channel inhibitors. Assay and Drug Development Technologies. 6: 195-212
Richards KS, Swensen AM, Lipscombe D, et al. (2007) Novel CaV2.1 clone replicates many properties of Purkinje cell CaV2.1 current. The European Journal of Neuroscience. 26: 2950-61
Swensen AM, Bean BP. (2005) Robustness of burst firing in dissociated purkinje neurons with acute or long-term reductions in sodium conductance. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 3509-20
Swensen AM, Bean BP. (2003) Ionic mechanisms of burst firing in dissociated Purkinje neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 9650-63
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